July 2019
Volume 60, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2019
Decreased retinal sensitivity overlying melanocytic choroidal lesions evaluated by microperimetry
Author Affiliations & Notes
  • Rodrigo Jorge
    Ophthalmology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
  • Marina Labarrere
    Ophthalmology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
  • Andre Messias
    Ophthalmology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
  • Zelia Correa
    Ophthalmology, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland, United States
  • Footnotes
    Commercial Relationships   Rodrigo Jorge, None; Marina Labarrere, None; Andre Messias, None; Zelia Correa, None
  • Footnotes
    Support  CNPq Grant 305299/2015-8
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 726. doi:https://doi.org/
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    • Get Citation

      Rodrigo Jorge, Marina Labarrere, Andre Messias, Zelia Correa; Decreased retinal sensitivity overlying melanocytic choroidal lesions evaluated by microperimetry. Invest. Ophthalmol. Vis. Sci. 2019;60(9):726. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare the retinal sensitivity overlying choroid nevi located in the posterior pole and the threshold sensitivity of normal retina adjacent to these lesions using microperimetry

Methods : Prospective evaluation of 9 patients diagnosed with a small choroidal nevus submitted to a comprehensive ophthalmological evaluation that included measurement of best corrected visual acuity (BCVA), fundus photographs, optical coherence tomography with emphasis on enhanced depth imaging, and microperimetry of the region overlying the nevus and of a healthy adjacent region of the same eye using 4-2 strategy to calculate the sensitivity threshold at each site analyzed.

Results : All nine patients exhibited a choroidal nevus located between the arcades and with a mean (± SD) vertical diameter of 2.2± mm and a mean horizontal diameter of 2.3± mm. All nevus showed reduced sensitivity when compared to the sensitivity of the healthy area of the same eye. The mean (± SD) microperimetric retinal sensitivity threshold on the nevus was 20.06dB and it differed significantly from retinal sensitivity on adjacent retinas 24.95dB(p=0.01; t test). At the 6-month follow-up visit, sequential perimetry revealed similar statistical results when comparing the sensitivity threshold of the nevus area and the healthy retina with the baseline findings. There was no correlation between the mean area of nevus and the decrease in retinal sensitivity. (p>0.05).

Conclusions : Microperimetric retinal sensitivity threshold overlying choroidal nevi seems to be significantly decreased compared to healthy adjacent areas of the same eye.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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