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Lihua Gong, Jianmin Lin, Wei Xia, Fei Yuan; Prevalence of Diabetic Retinopathy in Chinese Adults With Type 2 Diabetes in the Rural Area of Shanghai. Invest. Ophthalmol. Vis. Sci. 2019;60(9):1095.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the prevalence of diabetic retinopathy (DR) in a Chinese population with type 2 diabetes.
A population-based cross-sectional study. Residents with type 2 diabetes from a village in the rural area of Shanghai were enrolled according to the resident health archives. The data including name, gender, ageand visual acuity were collected. Routine laboratory examinations were performed. Disc- and macula-centered retinal photographs were taken to assess DR. The diagnosis of DR and diabetic macular edema (DME) was made according to international clinical DR and DME disease severity scales. For the purpose of this study, the DR grade for each subject was based on the worse DR grade of the two eyes.
A total of 826 residents were recruited. The median (range) age of participants was 62 (33-83) years. The fundus photographs of 745 participants(90.2%)were of sufficiently good quality for grading. 116 participants were diagnosed with DR. The prevalence of DR was 15.57%, with mild, moderate, and severe non-proliferative retinopathy (NPDR) and proliferative retinopathy (PDR) to be 4.03%, 8.19%, 2.28% and 1.07%, respectively. 27 eyes (1.86%) were diagnosed with DME.FPG is correlated with the grading of DR (r=0.24, p<0.05). The participants diagnosed with DR had higher FPG (8.6±2.2mmol/l) than those without DR (10.3±3.2mmol/l) with statistical significance (t=6.94, p<0.05).In the binary logistic regression analysis, higher hemoglobin A1c(HbA1c)(OR, 1.402)and higher fasting plasma glucose(FPG)(OR, 1.131)were associated with the presence of DR.
The prevalence of DR among Chinese adults with type 2 diabetes in the rural area of Shanghai was 15.57%, in which non-proliferative DR was more common. HbA1c and FPG were asassociated with DR, suggesting themit arisk factorsof DR.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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