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Xia Gong, Wenyong Huang, Lanhua Wang, Wangting Li, Wei Wang; Sub-clinical Diabetic Macular Edema in Chinese Diabetes Patients: A Pilot Study.. Invest. Ophthalmol. Vis. Sci. 2019;60(9):1097.
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© ARVO (1962-2015); The Authors (2016-present)
This pilot, observational study aimed to select eyes with subclinical diabetic macular edema (SC-DME) and find out its relevant factors in Chinese diabetes patients.
1432 diabetes patients from Yuexiu District, Guangzhou City, China, had been voluntarily recruited by Nov. 21st, 2018. SC-DME is defined as macular center point thickness (CPT) in optical coherent tomography (OCT) ranges from 225 to 299 μm with no clinically apparent macular edema in fundus examination according to Diabetic Retinopathy Clinical Research Network. 7-field fundus photography was taken through pharmacologically dilated pupils for grading diabetic retinopathy. Optical biometric and systematic information was also collected. Participants who have other macular diseases or can not get clear images will be excluded.
1031 diabetes patients (1995 eyes) are included. Their average age is 65.6±8.31. 182 patients (17.7%，223 eyes) have SC-DME. The present of SC-DME is significantly related to R1 diabetic retinopathy (OR=0.07，P<0.01) and longer axial length (OR=1.47，P=0.001), while age, gender, blood pressure have no significant correlation with SC-DME.
About 1/6 of participants with diabetes have SC-DME. Diabetes patients with R1 retinopathy and longer axial length have a higher risk of developing SC-DME.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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