July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Concordance between color photo interpretation of the optic nerve and an Unsupervised Learning Algorithm to determine optic nerve damage
Author Affiliations & Notes
  • Sandra Belalcazar
    Fundacion Oftalmologica Nacional , Bogota, Colombia
  • VANESSA PATRICIA CARPIO ROSSO
    Fundacion Oftalmologica Nacional , Bogota, Colombia
  • Shirley Margarita Rosenstiehl Col�n
    Fundacion Oftalmologica Nacional , Bogota, Colombia
  • Oscar Julian Perdomo Charry
    Universidad Nacional, Bogota, Colombia
  • Fabio Augusto Gonzalez
    Universidad Nacional, Bogota, Colombia
  • Hernan Andres Rios
    Fundacion Oftalmologica Nacional , Bogota, Colombia
  • Claudia Carbajal
    Fundacion Oftalmologica Nacional , Bogota, Colombia
  • Footnotes
    Commercial Relationships   Sandra Belalcazar, None; VANESSA CARPIO ROSSO, None; Shirley Margarita Rosenstiehl Col�n, None; Oscar Perdomo Charry, None; Fabio Gonzalez, None; Hernan Rios, None; Claudia Carbajal, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1469. doi:
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      Sandra Belalcazar, VANESSA PATRICIA CARPIO ROSSO, Shirley Margarita Rosenstiehl Col�n, Oscar Julian Perdomo Charry, Fabio Augusto Gonzalez, Hernan Andres Rios, Claudia Carbajal; Concordance between color photo interpretation of the optic nerve and an Unsupervised Learning Algorithm to determine optic nerve damage. Invest. Ophthalmol. Vis. Sci. 2019;60(9):1469.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the concordance between an Unsupervised Learning Algorithm and eye fundus color photos interpretation by a specialist for the identification of the optic disc damage.

Methods : Cross-sectional study of diagnostic concordance for an Unsupervised Learning Algorithm was made. The Cohen's kappa coefficient was calculated for identification of the optic disc damage in eye fundus color photos and were assessed according to Armaly's cup/disc ratio classification.

Results : The Unsupervised Learning Algorithm evaluated 689 color optic disc images of subjects classified as: healthy (no damage), mild, moderate and severe damage. The second stage is composed of a k-means classifier using the first dense layer with 4096 units to cluster the extracted features in four groups. Obtained a performance measured of Cohen's kappa coefficient of 0,47, 0,82, 0,71 and 0,74 respectively. While classifying the images in two groups: Healthy and with damage, we found a Cohen's kappa coefficient of 0,70.

Conclusions : The Unsupervised Learning Algorithm for the classification of optic disc damage on color fundus photos showed a good concordance with the one done by the glaucoma specialist, using Armaly's cup/disc ratio classification. The concordance was better when the classification only included optic discs with damage (mild, moderate and severe).

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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