Abstract
Purpose :
To describe the clinical and Optic Coherence Tomography findings in patients after Simple Limbal epithelial Transplantation (SLET).
Methods :
This was a descriptive, longitudinal case series study. We included 5 patients that underwent SLET surgery. In 3 cases the stem cell deficiency was secondary to ocular burns, and two cases to immune disorder. Anterior Segment-Optic Coherence Tomography and Clinical Pictures were taken in patients before and after SLET at first and third month. Images were analyzed, described and related with clinical findings.
Results :
Before SLET,all patients showed a grade of corneal conjuntivalization, on OCT scan was observed like an hyperreflectic irregular area over corneal stroma. Corneal stroma showed a grade of opacity, which was seen like a zone with increase of reflectivity. Endotelium was observed as a line of higher reflectivity. One month after SLET, the limbal fragments were observed as an hyporreflectic area, surrounded by an hyperreflectic border, and the amniotic membrane like an hyperreflectic line over an hyporreflectic transition zone between stroma. At third month, we found the amniotic membrane and fragments integrated. In some cases, the surface was restored and the epitelium was observed like hyperreflectic line respect stroma. The stroma and endothelium showed the same caracteristics described at first month.
Conclusions :
OCT made possible to describe and relate it with the clinical evolution in patients post SLET, as well as to observe the caracteristics of limbal fragments, the presence or absence of epitelium, the endothelium and corneal stroma changes.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.