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Gyulli Kazakbaeva, Mukharram Bikbov, Timur Gilmanshin, Rinat Zainullin, Ellina Rakhimova, Kamilla Safiullina, Songhomitra Panda-Jonas, Iulia Rusakova, Natalia Bolshakova, Jost B Jonas; Prevalence and associated factors of glaucoma in a Russian Population. The Ural Eye and Medical Study. Invest. Ophthalmol. Vis. Sci. 2019;60(9):1973.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the prevalence and associated factors of glaucoma in a Russian population.
The Ural Eye and Medical Study (UEMS) is a population-based study performed in the city of Ufa/Russia and in villages at a distance of 65 km from Ufa. The inclusion criterion was an age of 40+ years. Glaucomatous optic neuropathy was diagnosed on optic disc photographs according to the International Society of Geographical and Epidemiological Ophthalmology (ISGEO) criteria.
Out of a population of 7328 eligible individuals, 5899 individuals (2580 (43.7%) men) (participation rate:80.5%) participated (mean age:59.0±10.7 years (range:40-94 years)).Assessable optic disc photographs were available for 4298 (72.9%) participants with a mean age of 58.6±10.5 years (range:40.94 years) and mean axial length of 23.3±1.1 mm. Glaucomatous optic neuropathy was present in 291/4298 participants or 6.8% (95% confidence interval (CI): 6.0,7.5). A higher glaucoma prevalence was significantly associated with higher intraocular pressure (P<0.001;OR:1.30; 95%CI:1.25,1.34), older age (P<0.001; odds ratio (OR): 1.08; 95%CI:1.06,1.09), urban region of habitation (P<0.001;OR:0.44;95%CI:0.33,0.59), longer axial length (P<0.001;OR:1.33; 95%CI:1.19,1.49), and male gender (P=0.006;OR:0.67; 95%CI:0.51,0.89). In that model, glaucoma prevalence was not significantly additionally associated with central corneal thickness (P=0.22), systolic (P=0.43) or diastolic (P=0.95) blood pressure.
In this typical, ethnically mixed, urban and rural Russian population aged 40+ years, the glaucoma prevalence was 6.8% (95%CI:6.0,7.5) with the main associated factors of higher intraocular pressure, older age, urban region of habitation, longer axial length and male gender while central corneal thickness and blood pressure were not significantly correlated.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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