July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Ten-year history of eyes with Retrodots – Monzen Eye Study –
Author Affiliations & Notes
  • Hiroshi Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Eri Shibuya
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Norihiro Mita
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Hisanori Miyashita
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Naoki Tanimura
    Shinseikai Toyama Hospital, Japan
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Teppei Shibata
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Hidetoshi Ishida
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Atsushi Arimoto
    Anamizu General Hospital, Japan
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Kenta Hagihara
    Ushitsu General Hospital, Japan
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Eri Kubo
    Department of Ophthalmology, Kanazawa Medical University, Kahoku-gun, ISHIKAWA, Japan
  • Footnotes
    Commercial Relationships   Hiroshi Sasaki, None; Eri Shibuya, None; Norihiro Mita, None; Hisanori Miyashita, None; Naoki Tanimura, None; Teppei Shibata, None; Hidetoshi Ishida, None; Atsushi Arimoto, None; Kenta Hagihara, None; Eri Kubo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 2071. doi:https://doi.org/
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      Hiroshi Sasaki, Eri Shibuya, Norihiro Mita, Hisanori Miyashita, Naoki Tanimura, Teppei Shibata, Hidetoshi Ishida, Atsushi Arimoto, Kenta Hagihara, Eri Kubo; Ten-year history of eyes with Retrodots – Monzen Eye Study –. Invest. Ophthalmol. Vis. Sci. 2019;60(9):2071. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : We investigated the 10-year history of Japanese eyes with Retrodots (RD).

Methods : Subjects comprised 435 eyes of 221 participants (158 of 81 males, 277 of 140 females, average age: 66.9±6.1 years, average follow-up: 10.1±0.9 years) of Monzen Eye Study, ongoing longitudinal epidemiological study of residents aged over 50 years living in Monzen town. Lens findings under maximal mydriasis were documented by one ophthalmologist with change in Kanazawa Medical University Classification and Grading System RD grade of 1 or over defined as progression. We examined risk of incidence and progression of RD with age, axial length and refraction (spherical equivalent) at baseline, gender, and refractive change at 10-year follow-up in a logistic regression model.

Results : Cataract surgery rates at 10-year follow-up were; 9.7% in eyes with transparent lens, 20.0% in eyes with only RD, 43.7% in eyes with opacities other than RD, and 62.9% in eyes with opacities plus RD, at baseline, respectively. RD incidence at 10-year follow-up increased with age (29.8% in 50s, 38.9% in 60s, and 61.2% in 70s and older at baseline) and was higher in males (36.7%) than females (14.5%). Incidence of RD was higher in hyperopic (48.3%) than myopic eyes (23.5%), with more eyes progressing to myopia over -1.0D among hyperopic (75.0%) than myopic eyes (26.5%). Incidence of RD increased 1.1-fold as age increased by 1 year (p<0.001). Among eyes with RD at baseline, surgery and progression rates at 10 years were higher in hyperopic (59.1% and 55.6%) than myopic eyes (46.7% and 42.9%), respectively (p<0.05). Risk of RD progression tended to be around 1.6-fold increased as refraction at baseline increased by 1D.

Conclusions : Incidence of RD is high in elderly hyperopic eyes. Ten years’ progression of RD and the surgery rate is high in hyperopic eyes with RD at baseline.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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