July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
The Change in corneal anterior-posterior area ratio after penetrating keratoplasty with keratoconus by using anterior segment optical coherence tomography
Author Affiliations & Notes
  • GAKU ISHIDA
    Kyoto prefectural university of medicine, Kyoto, Japan
  • Koji Kitazawa
    Kyoto prefectural university of medicine, Kyoto, Japan
  • Motohiro Itoi
    Kyoto prefectural university of medicine, Kyoto, Japan
  • Tsutomu Inatomi
    Kyoto prefectural university of medicine, Kyoto, Japan
  • Shigeru Kinoshita
    Kyoto prefectural university of medicine, Kyoto, Japan
  • Chie Sotozono
    Kyoto prefectural university of medicine, Kyoto, Japan
  • Footnotes
    Commercial Relationships   GAKU ISHIDA, None; Koji Kitazawa, None; Motohiro Itoi, None; Tsutomu Inatomi, None; Shigeru Kinoshita, HOYA (F), KOWA (F), SANTEN (F), SENJU (F); Chie Sotozono, ALCON (F), AMO (F), HOYA (F), SANTEN (F), SENJU (F)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 2119. doi:https://doi.org/
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      GAKU ISHIDA, Koji Kitazawa, Motohiro Itoi, Tsutomu Inatomi, Shigeru Kinoshita, Chie Sotozono; The Change in corneal anterior-posterior area ratio after penetrating keratoplasty with keratoconus by using anterior segment optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2019;60(9):2119. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : We previously reported that anterior and posterior corneal surface area imbalance in the pathological change of keratoconus by using anterior segment optical coherence tomography (SS-1000 CASIA; Tomey Corporation, Nagoya, Japan) (Kitazawa K et al. Scientific Report, 2018)In this study we compared changes of anterior and posterior corneal surface area ration after penetrating keratoplasty(PK) with keratoconus

Methods : This study involved 6 eyes of 6 subjects (58±13.24years old) seen at the Baptist Eye Institute and who were underwent PK with keratoconus. The study was performed in accordance with the tenets set forth in the Declaration of Helsinki, and was approved by the Kyoto Ethics Review Committee, Kyoto, Japan. The corneal anterior surface area (As), posterior surface area (Ps), As and Ps area ratio of 5 mm, 6 mm, 7 mm diameter were calculated from Elevation map at 6 months, 1, 2 , 3 years after PK by using AS-OCT. We compared statistically the time course of changes.

Results :
As (mm)of 5 mm, 6 mm, and 7 mm diameter was after 6 month (20.03, 29.03, 39.89) after 1 year (19.24, 26.61, 34.39) ,after 2 year (19.97, 28.64, 38.86),and after 3years( 20.11, 29.76, 40.28). Ps was after 6month (9.51, 26.78, 34.19)after 1 years (20.29, 28.64, 38.86) ,after 2 year (20.37, 29.57, 40.74),and after 3 years (20.42, 29.76, 41,15). As/Ps was after 6 month (0.9863, 0.9943, 1.00697) after 1 year (0.9841, 0.9872, 0.99) ,after 2 year (0.983, 0.981, 0.979),and after 3years( 0.984, 0.981, 0.979) As / Ps decreased significantly after PK at 6 and 7mm diameter. (P <0.03, P <0.001)

Conclusions :
The corneal surface area of the keratoconus gently changes after penetrating keratoplasty.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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