July 2019
Volume 60, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2019
High intraocular pressure in the view of the risk of open angle glaucoma in Korean; Korea National Health and Nutrition Examination Survey
Author Affiliations & Notes
  • Joon Mo Kim
    Ophthalmology, Kangbuk Samsung Hospital, Seoul, Korea (the Republic of)
  • Ko Eun Kim
    Ophthalmology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea (the Republic of)
  • Dae Hwan Shin
    Ophthalmology, Kangbuk Samsung Hospital, Seoul, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Joon Mo Kim, None; Ko Eun Kim, None; Dae Hwan Shin, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 2413. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Joon Mo Kim, Ko Eun Kim, Dae Hwan Shin; High intraocular pressure in the view of the risk of open angle glaucoma in Korean; Korea National Health and Nutrition Examination Survey. Invest. Ophthalmol. Vis. Sci. 2019;60(9):2413. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Currently, the most important risk factor for development of open angle glaucoma(OAG) is regarded as high intraocular pressure (IOP). In general, normal IOP range was 10 mmHg to 21 mmHg that was mean IOP with 2 standard deviation range. According to this traditional criteria, definition of high IOP is regarded as more than 21 mmHg. However, the IOP may vary by race, gender, or many other factors. In this study, we investigated the definition of the high IOP which was associated with the risk of the development of OAG with population-based, cross-sectional survey.

Methods : This analysis was performed with data from the data of the Korea National Health and Nutrition Examination Survey between 2010 and 2011. Data on demographics, comorbidities, and health-related behaviors were obtained, and comprehensive ophthalmic examinations were performed. According to the IOP, participants were divided into two subgroups (higher and lower). For each dividing, we computed prevalence of OAG for each group and analyzed with a t-test statistic, and the corresponding P values were adjusted for multiple testing. Optimal cut-off IOP value for dividing was determined that yielded the minimum P value. Multivariate regression analysis (adjusting for age, sex, diabetes, systemic hypertension, body mass index, serum cholesterol) was used to assess the optimal cutoff value of IOP associated with the development of OAG.

Results : A total of 7,656 participants (Male; OAG (193): control (3,045) vs Female; OAG (166): control (4,252)) were included in the analyses. In terms of the prevalence of OAG, significant cutoff value of low limit was 14mmHg in male (OR=0.68, 95% CI: 0.40 ~ 0.99, p=0.043) and 16mmHg in female (OR=0.47, 95% CI: 0.27 ~ 0.81, p=0.007), and significant cutoff value of high limit was 19mmHg in male subjects (OR=2.80, 95% CI: 1.27 ~ 6.16, p=0.011) and 18mmHg in female subjects (OR=2.65, 95% CI:1.32 ~ 5.32, p=0.006).

Conclusions : Considering the risk of the development of OAG, the IOP greater than 19mmHg in male and 18mmHg in female appears to be a high IOP in Korean.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×