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Yusuke Manabe, Akira Sawada, Tetsuya Yamamoto; Location in glaucomatous visual field loss vulnerable to posture-induced intraocular pressure changes. Invest. Ophthalmol. Vis. Sci. 2019;60(9):2415. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To seek for location in glaucomatous visual field loss vulnerable to posture-induced intraocular pressure (IOP) changes
We investigated 94 eyes with naïve normal tension glaucoma. All the eyes were satisfied with Anderson-Patella’s criteria on two consecutive visual field tests. The IOP was measured in the sitting and the lateral decubitus position with an Icare rebound tonometer. Visual field tests were performed with a Humphrey Field Analyzer with a 30-2 test pattern with Swedish Interactive Threshold Algorithm standard strategies. The total deviation (TD) map values of 76 tested pointed were used for analyzes. A regression analysis was conducted to assess a relationship between TD and posture-induced IOP changes.
The mean age was 53.3 ± 7.7 years. There were 55 women and 39 men. The mean IOP with an Icare rebound tonometer was 15.5 ± 6.5 mmHg in the sitting position and 18.7 ± 6.6 mmHg in the lateral decubitus position. This postural IOP difference was +3.3 ± 2.3 mmHg (P<0.001) with a range of -0.3 to 7.7 mmHg. There was a significant negative correlation between TD and posture-induced IOP changes in 4 contiguous central points located in just above the horizontal meridian.
Our result indicates that IOP variation might be related to glaucomatous visual field defect in closer to fixations.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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