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Denise Loya, Julio C Hernandez, Paloma Lopez, Guillermo Garcia-delaRosa, Jorge E Valdez; Assessment of dry eye parameters after corneal refractive surgery in Mexican patients. Invest. Ophthalmol. Vis. Sci. 2019;60(9):2745.
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© ARVO (1962-2015); The Authors (2016-present)
To report the correlation between OSDI and dry eye parameters in Mexican patients after corneal refractive surgery
Cross-sectional study of patients that presented to consultation with dry eye symptoms and history of corneal refractive surgery between June 2017 and November 2018 were included. Tear meniscus height (TMH), First noninvasive keratographic tear breakup time (NIBUT-F), Average noninvasive tear breakup time (NIBUT-Ave) ocular redness and meibography were measured using the (OCULUS Keratograph ®5M). Ocular Surface Disease Index (OSDI) questionnaire was performed. Statistical analysis was performed using SPSS software version 23.0 (SPSS Inc.)
102 eyes (51 patients) were included, mean age of 39.70 years±13.54, 66.7% were female. 88.2% had history of LASIK and 11.8% of PRK. Dry eye parameters evaluation was performed 31.41±50.24 months after corneal refractive surgery. Mean TMH was .20±.07mm, NIBUT-F and NIBUT-Ave were 7.19±4.90 and 11.47±5.21 seconds respectively. Ocular redness score was 1.23±0.47. Meibomian gland dropout of the upper lid and lower lid (grade 1 or 2 meiboscore) was observed in 58.9% and 66.7% of the eyes respectively. Mean OSDI score was 17.76±13.15 and a prevalence of 60.5% (OSDI >12).The correlation analysis showed that TMH had a weak correlation with NIBUT-Ave and ocular redness (r=.296, p=.002) (r=.215, p=.030) respectively. A weak correlation between age and ocular redness was observed (r=.283, p=004). A significant correlation was found within superior and inferior meibography (r=.518, p<.001) and between NIBUT-F and NIBUT-Ave (r=.737, p<.001). An association between female gender and age with a higher OSDI score was also observed (Χ2=13.036, p=.005), (Χ2=38.052, p=.034). No significant correlations were found between meiboscore and OSDI
Dry eye is one of the most common complication seen after corneal refractive surgery. Our results in Mexican population are in accordance with other studies that gender and age influences the risk of post refractive chronic dry eye. Even tough there is evidence that chronic dry eye is due to neuropathic factor, we found a correlation between TMH and NIBUT-Ave, ocular redness in addition to superior/ inferior meibography, NIBUT-F/NIBUT-Ave. Awareness of this association and further studies are needed for a better understanding of post refractive dry eye
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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