July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Cause of Death?: The relationship between visual impairment, ocular conditions and mortality
Author Affiliations & Notes
  • David J Lee
    University of Miami, South Miami, Florida, United States
  • Footnotes
    Commercial Relationships   David Lee, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 2838. doi:
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      David J Lee; Cause of Death?: The relationship between visual impairment, ocular conditions and mortality. Invest. Ophthalmol. Vis. Sci. 2019;60(9):2838.

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      © ARVO (1962-2015); The Authors (2016-present)

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Presentation Description : Studies dating as far back as the 1930’s have reported associations between visual impairment, age-related ocular conditions and increased mortality. More recent meta-analyses of these accumulating studies have documented that persons living with visual impairment, cataract, and late AMD are at a small but significantly increased risk of mortality (pooled hazard ratio [HR] range: 1.20-1.55). Adults living with Type 1 or Type 2 diabetes and a diagnosis of diabetic retinopathy versus those without are at a larger increased risk of mortality (pooled HR: 2.57). A summary of findings from the field will be provided along with the introduction of a conceptual model that incorporates a life course perspective on the role of proximal and distal risk factor influences on the ocular system as a marker of aging processes which are in turn associated with increased mortality risk.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.


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