Abstract
Purpose :
To correlate subfoveal choriocapillaris (CC) flow density with age using spectral-domain optical coherence tomography angiography.
Methods :
183 eyes of 94 subjects (66 female, 28 male) were enrolled. Included were healthy subjects from 21 to 82 years without any history of vitreoretinal disease. Measurements were obtained with AngioVue software of the XR Avanti OCT device (OptoVue, Inc., Fremont, CA, USA). Significance was defined as p<.05.
Results :
The mean age was 43.43 +/- 17.63 years. Correlation between decreasing CC flow density and increasing age was significant (p<.001) with a mean yearly flow decrease of .026%. Subfoveal choroidal thickness (SCT) decreased with advancing age but did not reach a level of significance (p=.069).
Conclusions :
There is a significantly negative correlation between CC flow density and advancing age in healthy subjects, analyzing direct extracted in-built software values from a commercial SD-OCTA device.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.