July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Choriocapillaris flow density negatively correlates with advancing age in spectraldomain optical coherence tomography angiography
Author Affiliations & Notes
  • Christiane Frank
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Pauline Scherm
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Klaus Wehrmann
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Nikolaus Feucht
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Chris Lohmann
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Mathias Maier
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Moritz Pettenkofer
    Klinikum rechts der Isar, Technische Universität München, München, Germany
  • Footnotes
    Commercial Relationships   Christiane Frank, None; Pauline Scherm, None; Klaus Wehrmann, None; Nikolaus Feucht, None; Chris Lohmann, None; Mathias Maier, None; Moritz Pettenkofer, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3052. doi:
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      Christiane Frank, Pauline Scherm, Klaus Wehrmann, Nikolaus Feucht, Chris Lohmann, Mathias Maier, Moritz Pettenkofer; Choriocapillaris flow density negatively correlates with advancing age in spectraldomain optical coherence tomography angiography. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3052.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To correlate subfoveal choriocapillaris (CC) flow density with age using spectral-domain optical coherence tomography angiography.

Methods : 183 eyes of 94 subjects (66 female, 28 male) were enrolled. Included were healthy subjects from 21 to 82 years without any history of vitreoretinal disease. Measurements were obtained with AngioVue software of the XR Avanti OCT device (OptoVue, Inc., Fremont, CA, USA). Significance was defined as p<.05.

Results : The mean age was 43.43 +/- 17.63 years. Correlation between decreasing CC flow density and increasing age was significant (p<.001) with a mean yearly flow decrease of .026%. Subfoveal choroidal thickness (SCT) decreased with advancing age but did not reach a level of significance (p=.069).

Conclusions : There is a significantly negative correlation between CC flow density and advancing age in healthy subjects, analyzing direct extracted in-built software values from a commercial SD-OCTA device.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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