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Jose David Morales, Lihteh Wu; The Foveal Avascular Zone Area in Healthy Eyes Measured by Ocular Coherence Tomography Angiography Using a Full Spectrum Probabilistic Algorithm . Invest. Ophthalmol. Vis. Sci. 2019;60(9):3059.
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The aim of this study was to determine the size of the foveal avascular zone (FAZ) area by OCT angiography using a full spectrum probabilistic algorithm in eyes of patients without any ocular or systemic pathology.
The charts and records from healthy patients that were evaluated at Asociados de Mácula Vítreo y Retina de Costa Rica from January 2018 to October 2018 that underwent OCTA of the macular area were reviewed. All participants were examined with the Spectralis OCT2 (Heidelberg Engineering, Heidelberg, Germany, Heidelberg Eye Explorer software version 6.9.5). The OCTA consisted of a 10° x 10° cube of 512 A scans separated by 6 µm each with an ART of 5. The FAZ area of the superficial vascular complex (SVC) and the deep vascular complex (DVC) were measured manually using the caliper tool of the Spectralis OCTA software by 2 different observers at 3 different times.
A total of 234 eyes of 121 patients were included in this study. Mean age was 50 (15 to 89 years), 85 patients (70%) were female. The SVC FAZ mean area was 0.40 ± 0.12 mm2. The DVC FAZ mean area was 0.30 ±0.11 mm2. There was no difference in vascular complex measures between eyes (p< 0.0001). There is a tendency of the FAZ in both vascular complexes to increase with age (p< 0.0001). The mean FAZ areas in the SVC (p=0.00204) and DVC (p=0.0192) were larger in females.
The FAZ in both the SVC and the DVC increase with age in normal individuals. Women have a larger FAZ in both the SVC and DVC.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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