Abstract
Presentation Description :
Retinal pigment epithelial cells (RPE) are a source of soluble molecules that can select and program macrophages to promote immune tolerance and suppress inflammation. This has suggested that ocular immune privilege has a mechanism to select for macrophages programmed to have memory-tolerance. This talk will present the experimental examples of how the RPE select and induce macrophages to act as suppressor/tolerogenic APC, and as suppressors of inflammation.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.