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Jason Shen, Binbin Chen, Frank Spors, fanglong dong, dorcas tsang, Lance McNaughton, Donald J Egan; Accommodative Response Differences Among Single Vision and Multifocal Contact Lenses. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3721.
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© ARVO (1962-2015); The Authors (2016-present)
The purpose of this study is to investigate the effect of multifocal contact lenses on accommodative responses when giving sequentially changed accommodative stimuli.
A total of thirteen young adults (9 females and 4 males, 24.6 ± 2.21 years) with - 3.31 ± 2.3 D mean sphere and astigmatism less than 1.50 D participated in this study with the only left eye measured using a high-resolution Shack-Hartmann wavefront aberrometer. An internal Maltese Cross target was moving sequentially from distance to near optically (+0.5 D to -10 D) in 0.5 D steps while the aberrations up to the sixth Zernike order were recorded simultaneously. Measurements were repeated without correction (baseline, BL), and then when subject wore full correction Acuvue Oasys Single Vision (ASV), Proclear Multifocal D (center distance) with 2.50 diopter (D) add power (PMD), and ArtMost SoftOK (SOK) contact lenses. The eye’s sphero-cylindrical refractive error was determined from second order Zernike terms. A mixed-model analysis with post-hoc Tukey-Kramer adjustment was conducted in data analysis.
When wearing ASV lenses, differences in accommodative responses relative to baseline varied from -0.12 D to +0.49 D and were not statistically significant (p = 0.99). Accommodative responses with PMD and SOK were significantly different from baseline (p < 0.0001). SOK showed larger differences than PMD lenses (p < 0.0001). At distance, SOK lenses generated accommodative response differences of -1.14 ± 0.6 D relative to baseline, while for PMD lenses these differences were -1.05 ± 0.69 D. For a -2.5 D accommodative stimulus, SOK lenses showed differences of -1.61 ± 0.46 D relative to baseline, while for PMD lenses these differences were -1.23 ± 0.62 D. For -4.0 D accommodative stimulus, PMD and SOK had relative responses of -0.87 ± 0.43 D and -1.32 ± 0.51 D, respectively.
Our study indicates that Acuvue Oasys Single Vision contact lenses, worn by young adults, did not affect accommodative responses with various accommodative stimuli. Proclear Multifocal D contact lenses with 2.50 D add power and SoftOK multifocal contact lenses did result in more negative relative accommodative responses, which has the same effect as reduced accommodative lag. The responses may contribute to their effectiveness in myopia progression control.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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