July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Effect of the Hydrus microstent with combined phacoemulsification on intraocular pressure
Author Affiliations & Notes
  • Maria Katharina Casagrande
    Ophthalmology, University Hospital Hamburg Eppendorf, Hamburg, Germany
  • Leonie Meier
    Ophthalmology, University Hospital Hamburg Eppendorf, Hamburg, Germany
  • Sanaz Farrokhi
    Ophthalmology, University Hospital Hamburg Eppendorf, Hamburg, Germany
  • Martin Spitzer
    Ophthalmology, University Hospital Hamburg Eppendorf, Hamburg, Germany
  • Maren Klemm
    Ophthalmology, University Hospital Hamburg Eppendorf, Hamburg, Germany
  • Footnotes
    Commercial Relationships   Maria Casagrande, None; Leonie Meier, None; Sanaz Farrokhi, None; Martin Spitzer, None; Maren Klemm, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3740. doi:
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    • Get Citation

      Maria Katharina Casagrande, Leonie Meier, Sanaz Farrokhi, Martin Spitzer, Maren Klemm; Effect of the Hydrus microstent with combined phacoemulsification on intraocular pressure. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3740.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess safety and efficacy of the Hydrus microstent (Ivantis, Inc, Irvine, CA) with combined phacoemulsification in patients with open angle glaucoma (OAG).

Methods : This retrospective study evaluates the data of 38 eyes of 34 patients with open angle glaucoma scheduled for a Schlemm’s canal
microstent (Hydrus) with a combined phacoemulsification. Postoperative IOP and topical anti glaucomatous therapy were obtained at 1 day, 4 weeks, 3, 6, and 12 months. In addition, intra and postoperative complication were documented during the study period of 12 months.

Results : After implantation mean IOP decreased statistically significant throughout the follow up (preoperative: 17.42 mmHg ±4.14 SD, after 12 months 15.17 mmHg ±2.18 SD, p=0.018). Medication reduced from mean 2.67 ±1.35 (range 0 to 5) preoperatively to mean 0.89 ±1.13 range 0 to 3) after 12 months (p=0.001). In 2 patients implantation was not possible and they were excluded from the follow up. No device related adverse event occurred. Transient IOP elevation >21 mmHg was present in 8 patients. One patient had a significant hyphema and a single fibrinous anterior chamber reaction occurred.

Conclusions : The Hydrus microstent with combined phacoemulsification is a safe and effective tool in lowering IOP and reducing anti-glaucoma medication.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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