July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
New "Chameleon-like" Corneal Endothelial Image Pattern generated by Specular Microscope
Author Affiliations & Notes
  • Kenzo Tomishige
    Ophthalmology, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, São Paulo, Brazil
  • Gustavo C Caiado
    Ophthalmology, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, São Paulo, Brazil
  • Ricardo Holzchuh
    Ophthalmology, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, São Paulo, Brazil
  • Ivan Corso Teixeira
    Ophthalmology, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, São Paulo, Brazil
  • Fernando Cesar Abib
    Universidade Federal do Paraná, Brazil
  • Richard Y Hida
    Universidade de São Paulo, Brazil
  • Footnotes
    Commercial Relationships   Kenzo Tomishige, None; Gustavo C Caiado, None; Ricardo Holzchuh, None; Ivan Corso Teixeira, None; Fernando Abib, None; Richard Hida, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3836. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Kenzo Tomishige, Gustavo C Caiado, Ricardo Holzchuh, Ivan Corso Teixeira, Fernando Cesar Abib, Richard Y Hida; New "Chameleon-like" Corneal Endothelial Image Pattern generated by Specular Microscope. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3836.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Image pattern generated by corneal specular microscopy (CSMy) suggests different clinical conditions. Some abnormal endothelial mosaic patterns have already been described, such as: Cornea Guttata, Iridocorneal Endothelial Syndrome, Fuchs Endothelial Dystrophy and Posterior Polymorphous Corneal Dystrophy. The purpose of this study is to analyze the clinical conditions related to a specific endothelial mosaic pattern not yet described, named as Chameleon-like pattern.

Methods : A cross-sectional study based on images of 650 eyes of 650 patients generated by a corneal specular microscope was performed. Five images of each cornea were analyzed: (1) central; (2) superior; (3) inferior; (4) lateral; and (5) medial. Patients with known patterns were excluded from this study: normal pattern, presence of Ice cells, guttae, band or vesicle, or Fuchs Endothelial Dystrophy. All clinical conditions with endothelial mosaic patterns that showed at least one image showing two of the following characteristics, named as "Chameleon-like" pattern, were included in this study: (1) significant endothelial density variation in different images of the same cornea; (2) the presence of polymegathism, heterogeneous and focal pleomorphism in different images of the same cornea; (3) the presence of adhered structures in different images of the same cornea.

Results : "Chameleon-like" pattern were shown in 160 corneas (24.61%). The following clinical conditions were related to this pattern: 91 (56.88%) were post-operative patients; 43 (26.87%) were contact lens users; 12 (7.5%) with history of endotheliitis; 10 (6.25%) with non-guttate endothelial degeneration; 2 (1.25%) with history of stroma keratitis; 1 (0.62%) post-radiotherapy patient; and 1 (0.62%) patient with history of iris tumor.

Conclusions : The newly described endothelial mosaic "Chameleon-like" pattern generated by specular microscope was mainly found in post-operative patients.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×