July 2019
Volume 60, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2019
Comparison of Colour Fundus Photography and Ultra-wide field retinal imaging in the detection of choroidal naevi in an ageing population
Author Affiliations & Notes
  • Nicola B Quinn
    Queen's University Belfast, Belfast, United Kingdom
  • Sophia Rachael Halliday
    Queen's University Belfast, Belfast, United Kingdom
  • DAVID WRIGHT
    Queen's University Belfast, Belfast, United Kingdom
  • Usha Chakravarthy
    Queen's University Belfast, Belfast, United Kingdom
  • Tunde Peto
    Queen's University Belfast, Belfast, United Kingdom
  • Frank Kee
    Queen's University Belfast, Belfast, United Kingdom
  • Ian Young
    Queen's University Belfast, Belfast, United Kingdom
  • Bernadette McGuinness
    Queen's University Belfast, Belfast, United Kingdom
  • Ruth Hogg
    Queen's University Belfast, Belfast, United Kingdom
  • Footnotes
    Commercial Relationships   Nicola Quinn, Optos plc (F); Sophia Halliday, None; DAVID WRIGHT, None; Usha Chakravarthy, None; Tunde Peto, Optos plc (F); Frank Kee, None; Ian Young, None; Bernadette McGuinness, None; Ruth Hogg, Optos plc (F)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3955. doi:
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      Nicola B Quinn, Sophia Rachael Halliday, DAVID WRIGHT, Usha Chakravarthy, Tunde Peto, Frank Kee, Ian Young, Bernadette McGuinness, Ruth Hogg; Comparison of Colour Fundus Photography and Ultra-wide field retinal imaging in the detection of choroidal naevi in an ageing population. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3955.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the prevalence of choroidal naevi in a population based sample of ageing individuals in Northern Ireland and compare their detection using ultra-wide field retinal imaging (UWFI) and colour fundus photography (CFP).

Methods : UWFI (Optomap 200 TX) and CFP images (Canon CX-1, Tokyo, Japan) were obtained from the Northern Ireland Cohort of the Longitudinal Study of Aging (NICOLA Study) participants. The Optomap images were graded for the presence of choroidal naevi using the Manchester Grid (MG), which is composed of 400 cells, each approximately one disc area in size. The retina was divided into regions using defined x- and y-coordinates on the MG to determine the area of the retina corresponding to the CFP images. CFP images were graded for the presence of naevi using Oculab (V3.7.980) imaging platform. All discordant cases were adjudicated by a senior grader. Descriptive statistics were used to describe the prevalence and concordance between imaging modalities for choroidal naevi.

Results : Retinal imaging was available from 3393 participants (6270 eyes for CFP and 6153 eyes for UWF), aged 36-99 (mean 63 years, SD 9.01). In UWFI naevi were found in 486(7.9%) of eyes. In the area corresponding to the field of view of CFP naevi were found in 237 (3.8%) eyes from 103 participants using CFP whereas naevi were identified in 275 (4.5%) eyes using UWFI, from 243 participants. The Kappa value for this comparison was 0.96 indicating almost perfect agreement. In 2 eyes CFP detected naevi were UWFI didn’t, in 229 eyes naevi were detected on both UWFI and CFP and in 16 eyes naevi were detected on UWFI but were not detected on CFP.

Conclusions : Previously reported choroidal naevus prevalence rates (0.2% to 30%) vary widely due to different study populations, examination methods used etc. The prevalence rate found in this study was 3.8% and 4.5% for CFP and UWFI respectively. The detection of choroidal naevi using UWFI was superior to that off standard CFP. The reasons behind this may include; the appearance of naevi found on each imaging modality, the different use of lasers with each modality and artefacts present on the images.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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