Abstract
Purpose :
White dots syndromes and choroiditis are a group of entities that could be a diagnostic challenge because of the similar features among each other. We developed a movile device software to clinically guide the diagnostic probability in patients with white dots syndromes.
Methods :
We developed an application, which through predetermined clinical variables, throws the probability of a clinical diagnosis of one of the next syndromes: Multiple evanescent white dots syndrome(MEWDS), serpiginous choroiditis, acute multifocal placoid pigment epitheliopathy(AMPPE), multifocal choroiditis, punctate inner choroidopathy(PIC) and birdshot chorioretinopathy. The probability is presented in the software as a percentage and it comes with a brief revision of the entity with the highest probability. We clinically tested the application in three patients at our center.
Results :
Case 1: 45 year old woman with a -4.00sph for both eyes comes with a central scotoma of the right eye, multiple white lesions in choroid and EPR 100-300 micron large confined to the posterior pole with no vitritis were seen. Left eye was normal. Application diagnosis: PIC (83%).
Case 2: 23 year old male with bilateral progressive visual loss, multiple white lesions 1-2DD lare confined to the posterior pole, some with EPR atrophy were seen in both eyes. Application diagnosis: AMPPE (78%).
Case 3: 37 year old woman with a -3.50sph for both eyes comes with blurry vision an photopsias in her left eye, multiple discrete white dots in posterior pole and outer retina that dissapeared in 5 days were seen, also presented hyperemia of the optic nerve head, vitritis+, and granular aspect of the fovea. Right eye was normal. Application diagnosis: MEWDS (89%).
Conclusions :
The application is a practical and valuable tool for a quick clinical guidance of white dots syndromes. It does not substitute further tests like OCT or angiography.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.