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Mukharram Bikbov, Timur Gilmanshin, Rinat Zainullin, Gyulli Kazakbaeva, Ellina Rakhimova, Kamilla Safiullina, Songhomitra Panda-Jonas, Iulia Rusakova, Natalia Bolshakova, Guzel Bikbova, Jost B Jonas; Prevalence and associated factors of diabetic retinopathy in a Russian Population. The Ural Eye and Medical Study. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3959.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the prevalence and associated factors of diabetic retinopathy in a Russian population.
The Ural Eye and Medical Study (UEMS) is a population-based study performed in the city of Ufa/Russia and in villages in a distance of 65 km from Ufa. The inclusion criterion was an age of 40+ years. Diabetic retinopathy was diagnosed on fundus photographs.
Out of a population of 7328 eligible individuals, 5899 individuals (2580 (43.7%) men) (participation rate:80.5%) participated (mean age:59.0±10.7 years (range:40-94 years)). Assessable fundus photographs were available for 4900 (83.1%) participants. Diabetic retinopathy was detected in 101/4900 individuals or 2.1% (95% confidence interval (CI): 1.7, 2.5). In binary multivariable analysis, a higher prevalence of diabetic retinopathy was associated with older age (P<0.006; odds ratio (OR): 1.05; 95%CI: 1.02,1.07), higher glucose serum concentration (P<0.001;OR: 1.17; 95%CI:1.09,1.25), history of therapy with insulin (P<0.001;OR: 3.09; 95%CI:3.08,4.94), higher systolic blood pressure (P<0.001;OR: 1.03; 95%CI:1.01,1.04), and longer history of known diabetes (P<0.001;OR: 1.06; 95%CI:1.03,1.09). In that model, diabetic retinopathy prevalence was not associated with axial length (P=0.71), rural versus urban region of habitation (P=0.08), and serum concentration of triglycerides (P=0.26).
In this typical, ethnically mixed, urban and rural Russian population aged 40+ years, the prevalence of diabetic retinopathy was relatively low (101/4900 or 2.1% (95%:1.7, 2.5) and depended on known risk factors such as higher systolic blood pressure, longer duration of known diabetes, older age and worse metabolic control.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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