July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Central Retinal Venous Pressure in Asymmetric Primary Open Angle Glaucoma (POAG)
Author Affiliations & Notes
  • Lutz E Pillunat
    Dept of Ophthalmology, University Eye Hospital Dresden, Dresden, Germany
  • Robert Herber
    Dept of Ophthalmology, University Eye Hospital Dresden, Dresden, Germany
  • Clemens Carl
    Dept of Ophthalmology, University Eye Hospital Dresden, Dresden, Germany
  • Karin R Pillunat
    Dept of Ophthalmology, University Eye Hospital Dresden, Dresden, Germany
  • Footnotes
    Commercial Relationships   Lutz Pillunat, None; Robert Herber, None; Clemens Carl, None; Karin Pillunat, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 4271. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Lutz E Pillunat, Robert Herber, Clemens Carl, Karin R Pillunat; Central Retinal Venous Pressure in Asymmetric Primary Open Angle Glaucoma (POAG). Invest. Ophthalmol. Vis. Sci. 2019;60(9):4271.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Elevated central retinal venous pressure (CRVP) leads to reduced ocular perfusion pressures which might be responsible for further progression in glaucoma. Aim of the present study was to evaluate whether an elevated CRVP is associated with visual field damage in asymmetric glaucoma.

Methods : 21 patients suffering from POAG were included. Asymmetric glaucoma damage was defined as a difference of >5 dB mean deviation (MD) in Humphrey 30-2 visual fields comparing both eyes of one patient. CRVP was measured by Ophthalmodynamometry. Elevated CRVP was defined as > 5mmHg higher compared to IOP. Furthermore intraocular pressure (IOP) and retinal nerve fibre layer thickness (Spectralis OCT, Heidelberg Engineering) were evaluated. For statistical analysis the Mann-Whitney-U test and the Spearman Correlation was applied.

Results : The mean visual field defect was 5,03 dB in less affected eyes and respectively 16,91 dB in more affected eyes (p< 0.001). IOP showed no significant differences between more or less affected eyes (12,83 mmHg/12,57 mmHg). CRVP showed also no significant differences between eyes suffering from early or advanced visual field damage (20,54 mmHg/19,83 mmHg). Elevated CRVP was, however, significantly correlated with structural damage. Retinal nerve fiber layer thickness was found to be significantly less in eyes with elevated CRVP (66,52 um/81,31 um/ p=0,049).

Conclusions : The results of the present study show that elevated CRVP is not necessarily correlated with functional glaucoma damage (visual field). Structural damage, however, might be a reason for a elevated CRVP and therefore the cause of reduced perfusion pressures in some POAG patients.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×