July 2019
Volume 60, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2019
Relationship between shape of foveal avascular zone determined by OCT angiography and metamorphopsia in epiretinal membrane patients
Author Affiliations & Notes
  • Hiroto Terasaki
    Kagoshima University, Japan, Kagoshima-shi, Kagoshima, Japan
    Seiunkai Hospital, Japan
  • Hideki Shiihara
    Kagoshima University, Japan, Kagoshima-shi, Kagoshima, Japan
  • Hidetaka Yamaji
    Shirai Eye Hospital, Japan
  • Toshihiko Uno
    Shirai Eye Hospital, Japan
  • Shinnosuke Yamaoka
    Graduate School of Science and Engineering, Kagoshima University, Japan
  • Mutsumi Watanabe
    Graduate School of Science and Engineering, Kagoshima University, Japan
  • Naoko Kakiuchi
    Kagoshima University, Japan, Kagoshima-shi, Kagoshima, Japan
  • Shozo Sonoda
    Kagoshima University, Japan, Kagoshima-shi, Kagoshima, Japan
  • Taiji Sakamoto
    Kagoshima University, Japan, Kagoshima-shi, Kagoshima, Japan
  • Footnotes
    Commercial Relationships   Hiroto Terasaki, None; Hideki Shiihara, None; Hidetaka Yamaji, None; Toshihiko Uno, None; Shinnosuke Yamaoka, None; Mutsumi Watanabe, None; Naoko Kakiuchi, None; Shozo Sonoda, None; Taiji Sakamoto, None
  • Footnotes
    Support  JSPS KAKENHI 17K16974
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 4533. doi:
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      Hiroto Terasaki, Hideki Shiihara, Hidetaka Yamaji, Toshihiko Uno, Shinnosuke Yamaoka, Mutsumi Watanabe, Naoko Kakiuchi, Shozo Sonoda, Taiji Sakamoto; Relationship between shape of foveal avascular zone determined by OCT angiography and metamorphopsia in epiretinal membrane patients. Invest. Ophthalmol. Vis. Sci. 2019;60(9):4533.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the relationship between the shape of foveal avascular zone (FAZ) determined by OCT angiography (OCTA) and metamorphopsia in epi-retinal membrane patients.

Methods : A retrospective cross-sectional case study was done including 54 eyes of 51 patients with ERM. Macular 3 x 3mm scan was recorded by PLEX-Elite 9000 (Carl-Zeiss, Dublin, CA). Area, circularity and eigen value determined by principal component analysis of the FAZ (whole retina) were manually calculated using ImageJ software (National Institutes of Health, USA). The relationship between the above parameters of FAZ and visual function such as logMAR visual acuity and the degree of metamorphopsia determined by M-chart (Inami,, Japan) were assessed by Spearman’s rank correlation coefficients.

Results : Mean age (±SD), VA and degree of metamorphopsia of the subjects were 69.6±8.2 years, 0.31±0.30 logMAR units and 0.49±0.42, respectively. Mean area, circularity, and eigen value were 0.137±0.084 mm2, 0.491±0.106 and 0.651±0.163, respectively. Although VA was not correlated with FAZ parameters, degree of metamorphopsia was significantly correlated with the area (R=-0.491, P=0.002), circularity (R=-0.385, P=0.004) and eigen value (R=-0.341, P=0.012). Multiple regression analysis showed that the area of FAZ was independently correlated with the degree of metamorphopsia.

Conclusions : Area and shape of FAZ might be predictive factors for metamorphopsia in ERM patients.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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