July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Vessel and perfusion analysis using optical coherence tomography angiography in acute central serous chorioretinopathy
Author Affiliations & Notes
  • Dominika Podkowinski
    Kepler University Clinic, Linz, Vienna, Austria
  • Bernhard Foessl
    Kepler University Clinic, Linz, Vienna, Austria
  • Anna-Sophie Mursch-Edlmayr
    Kepler University Clinic, Linz, Vienna, Austria
  • Sophie Beka
    Kepler University Clinic, Linz, Vienna, Austria
  • Michael Ring
    Johannes Kepler Universität, Linz, Austria
  • Matthias Bolz
    Kepler University Clinic, Linz, Vienna, Austria
  • Footnotes
    Commercial Relationships   Dominika Podkowinski, None; Bernhard Foessl, None; Anna-Sophie Mursch-Edlmayr, None; Sophie Beka, None; Michael Ring, None; Matthias Bolz, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 4554. doi:
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      Dominika Podkowinski, Bernhard Foessl, Anna-Sophie Mursch-Edlmayr, Sophie Beka, Michael Ring, Matthias Bolz; Vessel and perfusion analysis using optical coherence tomography angiography in acute central serous chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2019;60(9):4554.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Swept Source Optical coherence tomography (SS-OCTA) is a novel technique to visualize blood flow in retinal and choroidal vasculature. The aim of this study was to evaluate choroidal blood flow in patients with acute central serous chorioretinopathy (CSC) over the time period of 1 month.

Methods : In this prospective, cross-sectional study we included 14 patients with acute central serous chorioretinopathy undergoing standard ophthalmological examination, including OCTA and fluorescein angiography (FA) and indocyanine green (ICG) imaging. Patients were imaged with OCTA at baseline and month 1. Quantitative image analysis was performed using swept source OCT (SS-OCT) scans to determine SRD areas. Segmentations errors were corrected manually. Automated Vessel density analysis was performed for the macula and the areas with SRD present. Macula region and marked areas were compared between baseline and month 1 for each patient.

Results : The mean age of the patients was 44.07±8.75 years. All subjects were male and presented with serous retinal detachment (SRD) at baseline. In 13 patients SRD was present at month 1, 1 patient showed resorption of the SRD. There was no difference in vessel and perfusion density in the macula, and SRD/ non SRD between baseline and month 1 for each patients.

Conclusions : The novel technique of SS-OCTA provides valuable information about vascular perfusion status using a non-invasive approach. Patients with acute central serous chorioretinopathy show no difference in vascular and perfusion density in the choriocapillaris between baseline and month 1 in SRD/ non SRD areas and the macular region. Therefore no short time difference could be found in the vasculature in these patients using optical coherence tomography angiography.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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