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keiichiro tanaka, Tetsuju Sekiryu; Low Signal Intensity Structure in The Choroid Detected in Optical Coherence Tomography Angiography. Invest. Ophthalmol. Vis. Sci. 2019;60(9):5019.
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© ARVO (1962-2015); The Authors (2016-present)
We noticed low signal intensity tube-like structure (LTLS) along the choroidal vessel in both optical coherence tomography angiography (OCTA) and structural optical coherence tomography. The characteristics of LTLS was investigated in this study.
Retrospective observational study. 116 eyes of 77 patients (diabetic retinopathy, central serous chorioretinopathy (CSC), age related macular degeneration, branch retinal vein occlusion) were examined. The images in size 12x12 mm was taken by using swept source OCT-A (PLEX™ Elite9000; Carl Zeiss Meditec). The chracteristics of LTLS in multimodal imaging, OCT-S, fundus autofluorescence (FAF), fluorescein angiography (FA) and indocyanine green angiography (IA), were analyzed.
Fifteen (12.9%) of 116 eyes showed LTLS . There was no statistically significant difference between the eyes with and without LTLS in age, sex, logMAR, intraocular pressure, spherical equivalent and axial length. Nine (60%) of 15 eyes with CSC and Two (66%) of 3 fellow eyes with CSC showed LTLS. The incidence of LTLS in CSC was statistically significantly higher than that in the other diseases. LTLS showed iso-fluocescence to the surroundings in FA. IA showed hypofluorescence on LTLS in the early phase, and iso-fluorescence in the late phase. Intensity of FAF did not change on LTLS.
LTLS in OCTA may be inter choroidal space along the choroidal vessel isolated from the vessel because LTLS did not show remarkable changes in angiography. Since LTLS appeared frequently in CSC, LTLS might be interstitial fluid in the choroid.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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