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Kensuke Goto, Takeshi Iwase, Tomohiko Akahori, Hiroko Terasaki; Relationship between the retinal displacement and the thickness change after vitrectomy in MH eyes. Invest. Ophthalmol. Vis. Sci. 2019;60(9):5045.
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© ARVO (1962-2015); The Authors (2016-present)
The macular displacement after the vitrectomy with inner limiting membrane (ILM) peeling for idiopathic macular hole (MH) has been reported. We investigated whether the retinal thickness change is accompanied with the macular displacement.
Twenty eyes of 20 patients who received the vitrectomy with ILM peeling for MH at the Nagoya University Hospital were included. OCTA (Angioplex) was used to obtain 3mm × 3mm en face images before and 2, 8 weeks after the surgery. We measured the distance between the center of the optic disc and an easily identifiable bifurcation of the retinal vessels in the 4 quadrants (temporal, superior, nasal, and inferior). Spectral-domain OCT (Spectralis) was used to measure the retinal thickness at the point 1500μm away from the fovea at the same period. In measuring the thickness, four retinal layer thicknesses were measured: the nerve fiver layer to the inner nuclear layer (inner retina), the outer plexiform layer to the retinal pigment epithelium (RPE) (outer retina), the external limiting membrane (ELM) to the ellipsoid zone (EZ) (ELM-EZ), the EZ to the RPE (EZ-RPE). The relationship between the macular displacement and the retinal layer thickness change was analyzed.
The retina was significantly displaced nasally in all of the quadrants after Week 2 (p<0.001), whereas there were no significant differences in the displacement among postoperative periods. The temporal retinal thickness significantly decreased 2 weeks after the surgery (p=0.005). The inner retinal thickness in the temporal quadrant significantly decreased 2 and 8 weeks after the surgery (p=0.001, p=0.002, respectively). The outer retinal thickness in the nasal and inferior quadrants significantly increased 8 weeks after the surgery (p=0.008, p=0.004, respectively). The ELM-EZ thickness showed no significant changes, while the EZ-RPE thickness showed significantly thicker at Week 8 compared with before the surgery in all of the quadrants (all, p<0.05). The macular displacement was not correlated with the changes of retinal thickness in any layers.
The retinal layer thickness was significantly changed and the macula was significantly displaced after the surgery. However, the layer thickness changes were not correlated with the macular displacement, indicating that the postoperative retinal layer thickness changes would not be influenced by the retinal displacement.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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