Investigative Ophthalmology & Visual Science Cover Image for Volume 60, Issue 9
July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
“Cellular heterogeneity of human stem cell-derived RGCs”
Author Affiliations & Notes
  • Donald J Zack
    Ophthalmology, Wilmer Eye Inst, Johns Hopkins Univ, Baltimore, Maryland, United States
  • Footnotes
    Commercial Relationships   Donald Zack, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 5636. doi:
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    • Get Citation

      Donald J Zack; “Cellular heterogeneity of human stem cell-derived RGCs”. Invest. Ophthalmol. Vis. Sci. 2019;60(9):5636.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Presentation Description :
Investigations from a number of labs indicate that there are greater than thirty distinct subpopulations of mammalian retinal ganglion cells (RGCs). Studies also suggest that not only do these subpopulations different in the type of visual information that they convey, they also differ in their susceptibility to injury and in their regenerative capacity. The development of single cell transcriptomic technologies has made possible the molecular analysis of the RGC subpopulations, including human stem cell-derived RGCs, at the single cell level. This presentation will summarize recent advances and developments in tis area

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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