Abstract
Presentation Description :
Photoreceptor degeneration can rapidly lead to both activation of microglia and infiltation of monocytes that rapidly differentiate into macrophages within the retina. Using scRNAseq, the heterogeneity of these distinct populations is readily revealed, allowing functional subpopulations to be identified and the time course of monocyte differentiation to be defined in molecular terms within the retina.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.