July 2019
Volume 60, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2019
Association between Myopia and Lower Serum Zinc Status in Adolescents: The 2010 Korean National Health and Nutrition Examination Study
Author Affiliations & Notes
  • Niamh Burke
    Dublin Institute of Technology, Dublin 7, Ireland
  • john butler
    Dublin Institute of Technology, Dublin 7, Ireland
  • Ian Flitcroft
    Dublin Institute of Technology, Ireland
    Temple Street Children's University Hospital, Dublin, Ireland
  • James Loughman
    Dublin Institute of Technology, Dublin 7, Ireland
    African Vision Research Institute, Durban, South Africa
  • Footnotes
    Commercial Relationships   Niamh Burke, None; john butler, None; Ian Flitcroft, None; James Loughman, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 5826. doi:
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      Niamh Burke, john butler, Ian Flitcroft, James Loughman; Association between Myopia and Lower Serum Zinc Status in Adolescents: The 2010 Korean National Health and Nutrition Examination Study. Invest. Ophthalmol. Vis. Sci. 2019;60(9):5826.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : It has been suggested that low serum zinc levels may contribute to the development of myopia. The aim of this present study is to examine the association of serum zinc status with myopia.

Methods : Data from 304 adolescents aged 12-19 years, who participated in the Korean National Health and Nutrition Examination Study (KNHANES) from 2010 were used in this study. Multivariate logistic regression analysis was performed to examine the relationship between serum zinc status and myopia after adjustment for potential confounders. Additionally, the association between serum zinc and spherical equivalent refractive error (SER) was examined in the myopia group, through multiple linear regression.

Results : Among study participants, 84% were found to be myopic (<=-0.5 dioptres [D]). Although mean serum zinc was higher in the non-myopes [139.3 μg/dL] relative to myopes [138.1 μg/dL], the difference was not statistically significant (p=0.809). In multiple logistic regression analyses, serum zinc was not significantly associated with myopia, after adjustment for age, gender, residence, body mass index (BMI), family income, and recreational activity. In multiple linear regression, SER was not associated with serum zinc in the myopic group, after adjustment for confounding factors (p=0.629)

Conclusions : In contrast to previous Asian studies, lower serum zinc is not associated with the presence of myopia in Korean adolescents.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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