Abstract
Purpose :
To explore annual changes in refraction around the onset of myopic anisometropia in Chinese children.
Methods :
Medical records of anisomyopic patients from Zhongshan Ophthalmic Center between 2009 and 2018 were reviewed. Myopic anisometropia is defined as an interocular difference in SER (anisoSER) no less than 1.00D and a SER less than -0.50D in both eyes. Children were included with the age of 7 to 18 years at the first detection of myopic anisometropia. Years were defined (+1 or -1) relative to the examination at which the onset of anisomyopia was first identified. Data was organized according to eye with relative more or less myopia.
Results :
A total of 720 patients were included. The mean age was 12.61±2.44 years at the first detection of anisometropia. Annual change in ansioSER increased by 0.18±0.32D to 0.19±0.33D (both P<0.05) from three years to two years before the onset of anisomyopia. The highest progression (0.64±0.40D, P<0.001) was detected the year before onset. After the first identification of anisomyopia, mean annual change in anisoSER decreased and anisometropia trended to be stable (P>0.05). In individual analysis after the onset, the magnitude of anisometropia retained stable in 75.05% patients with annual anisoSER change of -0.25D/year to +0.25D/year, increased significantly in 12.66% patients with annual anisoSER change of 0.25D/year to 1.00D/year, and increased rapidly in only 0.95% patients with annual anisoSER change of 1.00D/year to 2.00D/year. Also, 11.34% patients had a decrease anisometropia with annual change in anisoSER between -0.25D/year to -1.00D/year. When anisometropia was defined as an anisoSER no less than 1.50D, annual change in anisoSER presented a similar variation patter
Conclusions :
Before the onset of myopic anisometropia, progression of anisoSER accelerate. After an anisometropia is established, anisoSER, on average, trend to be stable although individual variations exist.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.