July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Cause of superior detectability of multicolor SLO in detection of epiretinal membrane
Author Affiliations & Notes
  • Ryoh Funatsu
    Kagoshima University, Kagoshima-shi, Japan
  • Hiroto Terasaki
    Kagoshima University, Kagoshima-shi, Japan
  • Shozo Sonoda
    Kagoshima University, Kagoshima-shi, Japan
  • Hideki Shiihara
    Kagoshima University, Kagoshima-shi, Japan
  • Naoko Kakiuchi
    Kagoshima University, Kagoshima-shi, Japan
  • Footnotes
    Commercial Relationships   Ryoh Funatsu, None; Hiroto Terasaki, None; Shozo Sonoda, None; Hideki Shiihara, None; Naoko Kakiuchi, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6123. doi:
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      Ryoh Funatsu, Hiroto Terasaki, Shozo Sonoda, Hideki Shiihara, Naoko Kakiuchi; Cause of superior detectability of multicolor SLO in detection of epiretinal membrane. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6123.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : We reported that MultiColor scanning laser ophthalmoscope (MC-SLO, Heidelberg Engineering, Germany) was superior to color fundus image (CF) in detecting epiretinal membrane (ERM) (Funatsu, Terasaki et al. ARVO2018). However, its reason was not well understood. Thus the purpose of this study is to elucidate the mechanism or cause of making this difference.

Methods : A retrospective cross-sectional study of patients with ERM enrolled from May to November 2017 in Kagoshima University Hospital. Thirty five eyes of 32 patients were analyzed. Two different characters of ERM image such as membrane or retinal folds were semi-quantified by manual grading into three classes as the “visibility score”. (1-invisible, 2-Barely visible, 3-Visible). Visibility score of membrane and retinal folds between MC-SLO and CF was compared by the Steel-Dwass test separately.

Results : Visibility scores of the membrane fold were 1.80 ± 0.71 wth CF, 2.63 ± 0.54 with MC-SLO (P<0.01). In different wavelength of MC-SLO, it was 2.63 ± 0.54 by blue wavelength, 2.71 ± 0.51 by green wavelength and 1.17 ± 0.38 by red wavelength. Visibility score of retinal fold was 1.23 ± 0.49 with CF, 2.57 ± 0.61 with MC-SLO; 1.63 ± 0.60 by blue wavelength, 1.89 ± 0.68 by green wavelength and 1.68 ± 0.58 by red wavelength. The visibility score of membrane and retinal fold score in MC-SLO was significantly higher than that of CF. The difference of value between MC-SLO and CF was larger in membrane fold than retinal fold.

Conclusions : MC-SLO is superior to color fundus photography in detecting ERM. It may be due to better detectability on membrane fold than retinal fold.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.


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