July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Corneal Deflection Amplitude and Visual Field Progression in Primary Open-Angle Glaucoma
Author Affiliations & Notes
  • Youn Hea Jung
    Ophthalmology, Yeouido St. Mary's , Seoul, Korea (the Republic of)
  • Jung Il Moon
    Ophthalmology, Yeouido St. Mary's , Seoul, Korea (the Republic of)
  • Jeong Ah Shin
    Daejeon St. Mary's, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Youn Hea Jung, None; Jung Il Moon, None; Jeong Ah Shin, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6201. doi:
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    • Get Citation

      Youn Hea Jung, Jung Il Moon, Jeong Ah Shin; Corneal Deflection Amplitude and Visual Field Progression in Primary Open-Angle Glaucoma. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6201.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the relationship between corneal deflection amplitude and visual field progression rate in patients with primary open-angle glaucoma (POAG).

Methods : This study included 117 eyes of 72 patients with POAG followed for an average of 4.75 ± 1.23 years. Evaluation of visual field progression rate was performed using mean deviation of standard automated perimetry. Corneal deflection amplitude was measured using Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany). Linear mixed models were performed to determine the relationship between visual field progression rate and corneal deflection amplitude, intraocular pressure (IOP), and central corneal thickness (CCT) after adjusting for potentially confounding factors.

Results : Mean age was 56.50 ± 14.75 years. Baseline average mean deviation was -8.57 ± 9.12 dB and mean treated IOP was 14.31 ± 3.07 mmHg. Average deflection amplitude was 0.92 ± 0.15 mm. In both univariate and multivariate analysis, IOP (P = 0.027 and P < 0.001, respectively) and deflection amplitude (P = 0.034 and P < 0.001, respectively) significantly affected visual field progression rate. Eyes with high IOP and greater deflection amplitude showed increased risk of faster progression rate.

Conclusions : Corneal deflection amplitude was significantly related with glaucoma progression. Eyes with greater corneal deflection amplitude were at increased risk for having faster visual field progression rate in patients with POAG.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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