July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Outcomes of Simple Limbal Epithelial Transplant (SLET) for Treatment of Recurrent Pterygium
Author Affiliations & Notes
  • Tanya Trinh
    Ophthalmology, University of Toronto, Ontario, Canada
  • Nir Sorkin
    Ophthalmology, University of Toronto, Ontario, Canada
  • Zale Mednick
    Ophthalmology, University of Toronto, Ontario, Canada
  • Gisella Santaella
    Ophthalmology, University of Toronto, Ontario, Canada
  • Alexandre Telli
    Ophthalmology, University of Toronto, Ontario, Canada
  • Allan Slomovic
    Ophthalmology, University of Toronto, Ontario, Canada
  • Footnotes
    Commercial Relationships   Tanya Trinh, None; Nir Sorkin, None; Zale Mednick, None; Gisella Santaella, None; Alexandre Telli, None; Allan Slomovic, Abvie (C), Alcon Canada (C), Allergan (C), AMO (C), Bausch and Lomb (C), Santen (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6274. doi:
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      Tanya Trinh, Nir Sorkin, Zale Mednick, Gisella Santaella, Alexandre Telli, Allan Slomovic; Outcomes of Simple Limbal Epithelial Transplant (SLET) for Treatment of Recurrent Pterygium. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6274.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Recurrent pterygium remains a difficult problem to treat effectively with a plethora of techniques of varying success documented in the literature. We performed a retrospective interventional case series analysis assesing the outcomes of recurrent pterygium treated by a novel technique of simple limbal epithelial transplantatation (SLET).

Methods : A retrospective, interventional case series was performed including all patients with recurrent pterygium who underwent SLET surgery using ipsilateral donor tissue with minimum four months follow up at Toronto Western Hospital, Canada. Outcome measures included rates of recurrence, best spectacle corrected visual acuity (BSCVA) and post-operative complications including steroid response.

Results : Eight eyes of 8 patients were included. Mean age was 65.1 ± 13.6 years (range 36-79 years). Average follow up time was 13.9 ± 8.9 months (range 4-34 months). Average number of years since last pterygium surgery was 10 ±8.6 years. There were no intraoperative complications and all SLET donor harvests were ipsilateral and complete. No patients with a history of 1-2 pterygium surgeries had recurrences. Only two patients had more than two previous pterygium surgeries and these had recurrence at 3 and 5 months respectively. Fifty percent of patients experienced a steroid response. Two patients required a penetrating keratoplasty for corneal scarring to improve vision. No patients required a second SLET operation.

Conclusions : SLET is a novel technique that offers a new surgical procedure to address the problem of recurrent, aggressive pterygium. Larger series and longer term follow up is required to establish the efficacy against recurrence. Cases with three or more pterygium recurrences may require further management and concurrent management of limbal stem cell disease.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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