July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Translation and Validation of the 8-Item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among Japanese Soft Contact Lens Wearers: the J-CLDEQ-8
Author Affiliations & Notes
  • Shizuka Koh
    Innovative Visual Science, Osaka University Graduate School of Medicine, Suita, Japan
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan
  • Robin Chalmers
    Clinical Trial Consultant, Atlanta, Georgia, United States
  • Daijiro Kabata
    Medical Statistics, Osaka City University Graduate School of Medicine, Osaka, Japan
  • Ayumi Shintani
    Medical Statistics, Osaka City University Graduate School of Medicine, Osaka, Japan
  • Kohji Nishida
    Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan
  • Footnotes
    Commercial Relationships   Shizuka Koh, Johnson & Johnson (F), Menicon (R), Seed (F); Robin Chalmers, AcuFocus (C), Alcon (C), Bayer (C), Cooper Vision (F), Johnson & Johnson Vision Care (C), Visioneering. Inc (I), Vision Service Plan (C); Daijiro Kabata, None; Ayumi Shintani, None; Kohji Nishida, None
  • Footnotes
    Support  Investigator Initiated Study Grant by Johnson & Johnson Vision Care, Inc., Jacksonville, Florida
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6363. doi:
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      Shizuka Koh, Robin Chalmers, Daijiro Kabata, Ayumi Shintani, Kohji Nishida; Translation and Validation of the 8-Item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among Japanese Soft Contact Lens Wearers: the J-CLDEQ-8. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6363.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To translate and validate a Japanese version of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among a multi-center sample of Japanese speaking soft contact lens (SCL) wearers in Japan.

Methods : The study comprised two phases, 1) forward and backward translation of the CLDEQ-8 into Japanese, 2) cross-sectional validation of Japanese CLDEQ-8 (J-CLDEQ-8) among Japanese spherical disposable SCL wearers (daily disposable, 2 week, or monthly disposable) against their Overall Opinion of SCLs, and 3) repeatability testing in a subset of subjects.

Results : 300 subjects (118 males and 182 females) completed the J-CLDEQ-8 and anchoring Gestalt SCL questions. The J-CLDEQ-8 had a strong significant linear relationship to Overall Opinion of SCLs and the Self-Assessment of Eye Dryness. The Gestalt Eye Sensitivity question did not translate well in Japanese and the relationship between it and the J-CLDEQ-8 was not linear. A cutoff score of <11 points with the J-CLDEQ-8 related best to patients who reported “Excellent” or “Very Good” Overall Opinion of their SCLs, differing slightly from the North American CLDEQ-8 cutoff of <12 points. This <11 points cutoff yielded accuracy of 0.66, and a sensitivity of 0.67 and specificity of 0.66, very similar to the values for the original CLDEQ-8.

Conclusions : The J-CLDEQ-8 was capable of differentiating SCL wearers with different Overall Opinions of their SCLs, comparable to the original CLDEQ-8 in English.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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