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Cherie B Nau, Ellen Shorter, Amy Catherine Nau, Jennifer Swingle Fogt, Muriel Schornack, Jennifer S Harthan; Scleral lens reservoir densitometry changes in small and large diameter lenses after one hour of wear. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6372.
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To compare changes in the amount of debris in the tear reservoir behind small-diameter (14.9mm) and large-diameter (18.0mm) scleral lenses after one hour of wear.
A small-diameter (14.9mm, Blanchard OneFit, Manchester, NH) and a large-diameter (18.0mm, BostonSight; Needham, MA) scleral lens were fit on the right eye of 7 participants (age range 22-28 years; 25 ± 2 years, mean ± SD; 6 females) with normal ocular health. Lenses were fit according to manufacturer recommendations and filled with LacriPure (Menicon, North Billerica, MA). Each participant wore the small and large-diameter lens for one hour and the order of lens wear was randomized; four eyes wore the small-diameter lens first. Two Scheimpflug images (Pentacam, Oculus Inc.) were captured immediately after lens placement and again after one hour of wear. Measurements were then repeated with the other lens. The optical density of the fluid reservoir, measured midway between the anterior cornea surface and posterior lens surface, was assessed from vertical images using the Pentacam’s densitometry software. The average value of the two images for each time interval was calculated. The densitometry values at one hour were compared to baseline values using a paired t-test.
After one hour of large-diameter lens wear, optical density of the fluid reservoir increased from 5.2 ± 0.6% to 6.3 ± 2.4% (p=0.3, n=6). After one hour of small-diameter lens wear, fluid reservoir density increased from 4.8 ± 0.1% to 5.7 ± 0.5%(p = 0.005, n=7) There were no differences between initial densitometry with the large or small lenses at the initial measurement (p=0.07) or the one hour measurement (p=0.51).
Optical density of the post-lens fluid reservoir increases with both small and large-diameter scleral lens wear. Greater variability is found in fluid reservoir density after one hour of large-diameter lens wear. The post-lens fluid reservoir density behind a small diameter lens increases significantly after one hour.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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