Abstract
Purpose :
This study compares the visual performance of four presbyopia-correcting intraocular lenses (IOLs) with particular focus on the defocus curves.
Methods :
This retrospective, comparative study of four prospective studies included 105 patients after bilateral lens surgery with implantation of four presbyopia-correcting IOLs: diffractive panfocal PanOptix (N=27), diffractive trifocal AT LISA IOL (N=27), Mplus X segmental refractive (SegRef) IOL (N=25), Symfony extended depth of vision (EDOV) IOL (N=26). Uncorrected (UCVA) and distance-corrected visual acuity (DCVA) at 4 m, 80 cm, 60 cm (EDOV and panfocal IOL) and 40 cm, defocus curves, contrast sensitivity (CS), and spectacle independence (SI) were measured three months postoperatively.
Results :
Distance UCVA and DCVA showed no significant difference between the four groups. The EDOV IOL presented significantly worse near DCVA than the three other IOLs (p<0.001). The trifocal and EDOV IOL showed better intermediate DCVA compared to the panfocal and SegRef IOL at 80 cm (p<0.01). The EDOV and panfocal IOL demonstrated good intermediate DCVA at 60 cm with no significant difference.
Defocus curves of all IOLs presented no significant difference from 4 m to 2 m. The EDOV IOL showed significantly better VA from 1 m to 50 cm than the trifocal and SegRef IOL and from 1 m to 67 cm than the panfocal IOL. The panfocal IOL measured significantly better VA at 50 cm compared to all other IOLs. At 40 cm, the EDOV IOL revealed a significantly worse VA compared to the three other IOLs (p<0.001).
There was no significant difference between the CS (FACT) of the panfocal, trifocal and EDOV IOL. The SegRef IOL showed good CS (Optec 6500), however measured under differing target illuminations.
The spectacle independence reported a significant difference between groups: trifocal at 92.5%, panfocal at 96.3%, SegRef at 92%, EDOV at 70.8%, (p=0.022). Pairwise testing revealed a significant difference between the panfocal and EDOV IOL (p=0.019).
Conclusions :
All four presbyopia-correcting IOLs measured equally good DCVA with good CS and spectacle independence. The panfocal, trifocal, and SegRef IOL demonstrated better near DCVA than the EDOV IOL. However, the EDOV IOL showed better intermediate DCVA, and only the panfocal IOL presented better results at 50 cm.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.