July 2019
Volume 60, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2019
Comparison of defocus curves of four presbyopia-correcting intraocular lenses with four different designs: diffractive panfocal, diffractive trifocal, segmental refractive, and extended depth of vision
Author Affiliations & Notes
  • Myriam Susanne Boehm
    Ophthalmology, Goethe University Frankfurt, Frankfurt, Hessen, Germany
    Ophthalmology, Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States
  • Kerstin Petermann
    Ophthalmology, Goethe University Frankfurt, Frankfurt, Hessen, Germany
  • Eva Hemkeppler
    Ophthalmology, Goethe University Frankfurt, Frankfurt, Hessen, Germany
  • Thomas Kohnen
    Ophthalmology, Goethe University Frankfurt, Frankfurt, Hessen, Germany
    Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, United States
  • Footnotes
    Commercial Relationships   Myriam Boehm, Spouse- EMD Serono (E); Kerstin Petermann, None; Eva Hemkeppler, None; Thomas Kohnen, Allergan, Inc. (C), Bausch & Lomb GmbH (C), Carl Zeiss Meditec AG (F), Carl Zeiss Meditec AG (C), Geuder AG (C), Hoya Surgical Optics GmbH (F), Johnson & Johnson Vision Care, Inc. (Abbott Medical Optics, Inc.) (F), Johnson & Johnson Vision Care, Inc. (Abbott Medical Optics, Inc.) (C), Med Update Europe GmbH, Merck KGaA (C), Novartis AG (Alcon Laboratories, Inc.) (F), Novartis AG (Alcon Laboratories, Inc.) (C), Oculentis GmbH (F), Oculus Optikgerate GmbH (F), Oculus Optikgerate GmbH (C), Presbia PLC (C), Presbia PLC (F), Rayner Intraocular Lenses Ltd (C), Santen GmbH (C), Schwind Eye-Tech Solution (F), Schwind Eye-Tech Solutions (C), STAAR Surgical AG (C), TearLab Corp (C), Thea Pharma GmbH (C), Thieme Compliance GmbH (C), Ziemer Ophthalmology GmbH (C)
  • Footnotes
    Support  Peter Barry Fellowship Grant, ESCRS
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6467. doi:
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      Myriam Susanne Boehm, Kerstin Petermann, Eva Hemkeppler, Thomas Kohnen; Comparison of defocus curves of four presbyopia-correcting intraocular lenses with four different designs: diffractive panfocal, diffractive trifocal, segmental refractive, and extended depth of vision. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6467.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : This study compares the visual performance of four presbyopia-correcting intraocular lenses (IOLs) with particular focus on the defocus curves.

Methods : This retrospective, comparative study of four prospective studies included 105 patients after bilateral lens surgery with implantation of four presbyopia-correcting IOLs: diffractive panfocal PanOptix (N=27), diffractive trifocal AT LISA IOL (N=27), Mplus X segmental refractive (SegRef) IOL (N=25), Symfony extended depth of vision (EDOV) IOL (N=26). Uncorrected (UCVA) and distance-corrected visual acuity (DCVA) at 4 m, 80 cm, 60 cm (EDOV and panfocal IOL) and 40 cm, defocus curves, contrast sensitivity (CS), and spectacle independence (SI) were measured three months postoperatively.

Results : Distance UCVA and DCVA showed no significant difference between the four groups. The EDOV IOL presented significantly worse near DCVA than the three other IOLs (p<0.001). The trifocal and EDOV IOL showed better intermediate DCVA compared to the panfocal and SegRef IOL at 80 cm (p<0.01). The EDOV and panfocal IOL demonstrated good intermediate DCVA at 60 cm with no significant difference.
Defocus curves of all IOLs presented no significant difference from 4 m to 2 m. The EDOV IOL showed significantly better VA from 1 m to 50 cm than the trifocal and SegRef IOL and from 1 m to 67 cm than the panfocal IOL. The panfocal IOL measured significantly better VA at 50 cm compared to all other IOLs. At 40 cm, the EDOV IOL revealed a significantly worse VA compared to the three other IOLs (p<0.001).
There was no significant difference between the CS (FACT) of the panfocal, trifocal and EDOV IOL. The SegRef IOL showed good CS (Optec 6500), however measured under differing target illuminations.
The spectacle independence reported a significant difference between groups: trifocal at 92.5%, panfocal at 96.3%, SegRef at 92%, EDOV at 70.8%, (p=0.022). Pairwise testing revealed a significant difference between the panfocal and EDOV IOL (p=0.019).

Conclusions : All four presbyopia-correcting IOLs measured equally good DCVA with good CS and spectacle independence. The panfocal, trifocal, and SegRef IOL demonstrated better near DCVA than the EDOV IOL. However, the EDOV IOL showed better intermediate DCVA, and only the panfocal IOL presented better results at 50 cm.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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