July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Prevalence of dry eye syndrome in patients with type 2 diabetes
Author Affiliations & Notes
  • Jesus Guerrero
    Cornea, external diseases and refractive surgery, Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City, Mexico City, Mexico
  • Marisela Vazquez-Duran
    Ocular Epidemiology and Visual Health, Instituto de Oftalmolog�a Fundaci�n Conde de Valen, Delegacion Cuauhtemoc, DF, Mexico
  • Juan Carlos Serna-Ojeda
    Cornea, external diseases and refractive surgery, Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City, Mexico City, Mexico
  • Enrique O Graue-Hernandez
    Cornea, external diseases and refractive surgery, Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City, Mexico City, Mexico
  • Aida Jimenez-Corona
    Ocular Epidemiology and Visual Health, Instituto de Oftalmolog�a Fundaci�n Conde de Valen, Delegacion Cuauhtemoc, DF, Mexico
  • Footnotes
    Commercial Relationships   Jesus Guerrero, None; Marisela Vazquez-Duran, None; Juan Carlos Serna-Ojeda, None; Enrique Graue-Hernandez, None; Aida Jimenez-Corona, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6494. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Jesus Guerrero, Marisela Vazquez-Duran, Juan Carlos Serna-Ojeda, Enrique O Graue-Hernandez, Aida Jimenez-Corona; Prevalence of dry eye syndrome in patients with type 2 diabetes. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6494.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Type 2 diabetes is a highly prevalent disease in Mexico. Patients with this condition have abnormally high tear osmolarity and corneal neuropathy. This study aimed to determine the prevalence of dry eye syndrome (DES) in patients >50 years of age with diagnosis of type 2 diabetes.

Methods : A population-based study was carried out from 2016 to 2017, including 420 patients with previous diagnosis of diabetes or fasting plasma glucose >7.0 mmol/L (126 mg/dL). An ophthalmological examination was performed (superficial punctate keratitis and tear break-up time was evaluated) and symptoms were assessed using the 5-item dry eye questionnaire (DEQ-5) validated for DES, with a score ranging from 0 to 22. DES was classified as normal (<6), mild to moderate (6-11), and severe (>12).

Results : Of 420 patients [127 men (30.2%) and 293 women (69.8%); mean age 63.2 years (± 9.0)] and mean diabetes duration, of 14.08 +/- 11.72 years. 32.4% (n=136) had moderate DES, and 5% (n= 21) had severe DES. 67 patients had superficial punctate keratitis ( 15.95%) and 308 patients (73.33%) had tear break-up time <10 mm. Of the patients with severe DES, 28.6% had severe visual impairment compared with 7.2% of patients in those without no DES. Age > 65 years (OR= 1.65, 95%CI 1.41-1.94), hypertension (OR= 2.14, 95%CI 1.82-2.51), previous cataract surgery (OR=2.50, 95%CI 1.70-3.67), smoking (OR=1.57, 95%CI 1.21-2.03), and alcohol consumption (OR=1.23, 95%CI 1.00-1.50) were regarded as risk factors for DES (p< 0.05). Duration of diabetes >10 years (OR=1.34, 95%CI 0.87-2.05) and reduction of visual acuity (OR=1.48, 95%CI 0.89-2.45) were associated with DES, but showed no statistical significance (p> 0.05).

Conclusions : A strong association was observed between age >65 years and diminished visual acuity with DES. A complete ophthalmological examination in every patient with type 2 diabetes is recommended to rule out DES, given its impact on quality of life and visual implications.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×