Abstract
Purpose :
To evaluate the clinical characteristics, treatment and outcomes of corneal perforations related to rheumatoid arthritis.
Methods :
We retrospectively analyzed the data of 10 years from a large cohort of patients in a large reference center in Mexico City. Different variables were analyzed through a multiple logistic regression analysis for the probability to have a second procedure.
Results :
Sixty eyes of 51 patients were included with an average follow-up of 27 months. The most frequent perforation zones were central and paracentral. In a multiple logistic regression analysis, in patients treated with both an initial cyanoacrylate patch and those with a penetrating keratoplasty represented an increased probability of requiring a subsequent procedure. The most frequent complication was persistent epithelial defect in 40 eyes. Most of the patients had a combination of systemic steroid and immunosuppressive therapy.
Conclusions :
Corneal perforations related to rheumatoid arthritis generally require multiple interventions and a multidisciplinary approach.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.