July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Epidemiology of epiretinal membrane and macular edema in a large cohort of patients with uveitis
Author Affiliations & Notes
  • Chihiro Yanagida
    Tokyo Medical University, Tokyo, Japan
  • Yoshihiko Usui
    Tokyo Medical University, Tokyo, Japan
  • Ryosuke Mitsuhashi
    Tokyo Medical University, Tokyo, Japan
  • Kinya Tsubota
    Tokyo Medical University, Tokyo, Japan
  • naoya nezu
    Tokyo Medical University, Tokyo, Japan
  • Takeshi Kezuka
    Tokyo Medical University, Tokyo, Japan
  • Hiroshi Goto
    Tokyo Medical University, Tokyo, Japan
  • Footnotes
    Commercial Relationships   Chihiro Yanagida, None; Yoshihiko Usui, None; Ryosuke Mitsuhashi, None; Kinya Tsubota, None; naoya nezu, None; Takeshi Kezuka, None; Hiroshi Goto, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6679. doi:https://doi.org/
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    • Get Citation

      Chihiro Yanagida, Yoshihiko Usui, Ryosuke Mitsuhashi, Kinya Tsubota, naoya nezu, Takeshi Kezuka, Hiroshi Goto; Epidemiology of epiretinal membrane and macular edema in a large cohort of patients with uveitis. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6679. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Epiretinal membrane (ERM) and macular edema (ME) in patients with uveitis are can cause vision loss in the setting of uveitis. However, ERM and ME have not been studied in a large cohort of uveitis patients. In this study, we examined the prevalence and features of ERM and ME in patients with uveitis.

Methods : 1,318 patients (2,017 eyes) (; men 881 eyes in men, women 1,136 eyes in women), with mean average age of 47.1±19.1) years diagnosed with uveitis diagnosed at a single tertiary referral clinic between 2011 and 2016 were analyzed. The SS-OCT and/or SD-OCT images of all the subjects were reviewed to assess for ME and ERM.

Results : ME and ERM were detected in 7.4% and 7.8%, respectively, of all uveitis patients. The highest prevalence of ME (17.7%) and ERM (23.4%) was found in sarcoidosis. ME was also found in Behcet’s disease (13.3%), followed by[t1] unclassified granulomatous uveitis (15.3%), and unclassified non-granulomatous uveitis (15.3%); whereas the details of other diseases causing ERM is were unclassified granulomatous uveitis (15.1%), unclassified non-granulomatous uveitis (10.8%), and Behcet’s disease (10.1%).

Conclusions : The prevalence of ME and ERM is relatively high in sarcoidosis which is the representative granulomatous uveitis. The prevalence of ME and ERM seems toapparently differs among uveitis patients, suggesting that they may develop via different pathogenic mechanisms.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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