July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Ultra-wide field OCTA for evaluation of different stages of diabetic retinopathy
Author Affiliations & Notes
  • Kasra Attaran-Rezaei
    Ophthalmology & Visual Science, University of Washington, Seattle, Washington, United States
  • Steven Saraf
    Ophthalmology & Visual Science, University of Washington, Seattle, Washington, United States
  • Qinqin Zhang
    Ophthalmology & Visual Science, University of Washington, Seattle, Washington, United States
  • fupeng wang
    Ophthalmology & Visual Science, University of Washington, Seattle, Washington, United States
  • Ruikang K Wang
    Ophthalmology & Visual Science, University of Washington, Seattle, Washington, United States
  • Footnotes
    Commercial Relationships   Kasra Attaran-Rezaei, None; Steven Saraf, None; Qinqin Zhang, None; fupeng wang, None; Ruikang Wang, Zeiss (C)
  • Footnotes
    Support  research to prevent blindness
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3017. doi:https://doi.org/
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      Kasra Attaran-Rezaei, Steven Saraf, Qinqin Zhang, fupeng wang, Ruikang K Wang; Ultra-wide field OCTA for evaluation of different stages of diabetic retinopathy. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3017. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To use UW-OCTA for evaluation of retinal vascular density index, vessel capillary flow impairment zone, localize the area of neovascularization in patients with different stages of diabetic retinopathy (DR).

Methods : UW-OCTA was developed based on a 1060 nm swept source OCTA engine (Plex Elite, Carl Zeiss Meditec. Inc) running at100 kHz A-line rate with motion tracking mechanism. A montage scanning protocol was used to get UW-OCTA imaging, covering a field of view (FOV) of ~100 degrees. Complex OMAG algorithm was used to extract blood flow information including retina vascular density index, capillary flow impairment zone, localize the area of neovascularization in patients with diabetic retinopathy (DR).

Results : 44 patients in different stages of diabetic retinopathy underwent UW-OCTA. The UW-OCTA images provide distinct and detailed visualization of vascular networks over ~100-degree FOV and was able to localize the area of neovascularization located in the peripheral retina, retina vascular density index, and capillary flow impairment zone in patients with diabetic retinopathy (DR).

Conclusions : The UW-OCTA is a non invasive imaging modality that can be used to evaluate the peripheral retinal vascular density index, capillary flow impairment zone to detect early non proliferative diabetic retinopathy and localize the area of neovascularization in patients with proliferative diabetic retinopathy. The UW-OCTA can be used frequently to closely monitor the progression of diabetic retinopathy and evaluate the response to different treatment modality.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

 

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