July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
The impact of comorbid visual impairment and dementia on activity limitations in older adults
Author Affiliations & Notes
  • Nish Patel
    Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan, United States
  • Brian Stagg
    Duke University Eye Center, Durham, North Carolina, United States
  • Joshua R Ehrlich
    Ophthalmology and Visual Sciences, Center for Eye Policy and Innovation, University of Michigan, Ann Arbor, Michigan, United States
    Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, United States
  • Footnotes
    Commercial Relationships   Nish Patel, None; Brian Stagg, None; Joshua Ehrlich, None
  • Footnotes
    Support  The National Eye Institute (K23 EY027848) to JRE; a pilot grant to JRE from the Institute for Social Research at the University of Michigan funded by the National Institute on Aging (P30 AG012846); an unrestricted grant from Research to Prevent Blindness to the Department of Ophthalmology and Visual Sciences at the University of Michigan
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3635. doi:
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      Nish Patel, Brian Stagg, Joshua R Ehrlich; The impact of comorbid visual impairment and dementia on activity limitations in older adults. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3635.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The number of older adults affected by both visual impairment (VI) and dementia will increase due to aging of the population. Using data from a nationally-representative panel study, we sought to determine the impact of comorbid VI and dementia on activity limitations among older Americans. These findings will help inform interventions to address functional decline in this population.

Methods : Data from 2011-2016 from the National Health and Aging Trends Study, a nationally representative survey of Medicare enrollees age ≥ 65, were used to determine VI, dementia, and limitations in activities of daily living, instrumental activities of daily living, and mobility. VI was defined as self-reported difficulty recognizing someone across the street. Dementia was determined by the results of cognitive tests of memory, orientation, and executive function. Activity limitations were calculated by counting the number of activities for which participants required assistance from another person due to poor health or functioning. Multivariable regression was used to model the interaction between VI and dementia (Figure 1) to predict activity limitations, while adjusting for potential confounding factors and accounting for the complex survey design.

Results : A total of 11,558 participants contributed 28,717 observations. The adjusted predicted number of activity limitations for respondents with only VI was 1.34 (95% CI: 1.21-1.48). The predicted number of activity limitations for those without VI but with possible and probable dementia was 1.24 (95% CI: 1.14-1.33) and 2.02 (95% CI: 1.84-2.19), respectively. Respondents with both VI and probable dementia had fewer activity limitations (2.28, 95% CI: 2.03-2.53) than expected based on the independent contribution of each of these conditions (Figure 2).

Conclusions : Older adults with comorbid VI and dementia experienced a greater burden of activity limitations compared to those with only one of these impairments; however, probable dementia seemed to be the primary contributor. It is important to consider the impact of comorbidities like dementia when developing strategies to promote wellbeing for visually impaired older adults.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

Figure 1. Proposed model of the relationship among visual impairment, dementia, and activity limitations

Figure 1. Proposed model of the relationship among visual impairment, dementia, and activity limitations

 

Figure 2. Interaction of visual impairment and dementia in predicting activity limitations

Figure 2. Interaction of visual impairment and dementia in predicting activity limitations

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