July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Comparative Assessment of Outward Radial Forces Exerted by Hydrophobic Acrylic Intraocular Lenses and Capsular Tension Rings Under Common Degrees of Compression.
Author Affiliations & Notes
  • Andrew Pilon
    Bausch & Lomb, Placentia, California, United States
  • George Lau
    Bausch & Lomb, Placentia, California, United States
  • Valeri Kolesnitchenko
    Bausch & Lomb, Placentia, California, United States
  • Footnotes
    Commercial Relationships   Andrew Pilon, Bausch & Lomb (E); George Lau, Bausch & Lomb (E); Valeri Kolesnitchenko, Bausch & Lomb (E)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 3698. doi:
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      Andrew Pilon, George Lau, Valeri Kolesnitchenko; Comparative Assessment of Outward Radial Forces Exerted by Hydrophobic Acrylic Intraocular Lenses and Capsular Tension Rings Under Common Degrees of Compression.. Invest. Ophthalmol. Vis. Sci. 2019;60(9):3698.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the relative outward radial forces of various commercially-available hydrophobic acrylic intraocular lenses (IOLs) under common degrees of compression relative to an available capsular tension ring (CTR).

Methods : Ten representative samples of commercially-available IOLs (MX60 (Bausch & Lomb), MX60E (Bausch & Lomb), ZCB00 (Johnson & Johnson)) in addition to an equivalent sampling of a single variety of CTR (CTR10, FortifEYE, Bausch & Lomb) were placed in an compression force apparatus in their wet state. Outward radial forces were averaged across IOLs and CTRs tested using scenarios that mimic the physiologic range of capsular bag sizes (9.5, 10.0, 10.5, 11.0mm). Mid-powered IOLs (MX60: 20.0-20.5D, MX60E:20.0D, ZCB00: 14.0-26.0D) and a CTR with dimensions that fall within geometry being tested (uncompressed: 12.3mm, compressed: 10.0mm) were evaluated.

Results : The average radial outward compression forces observed were: at 11.0mm (MX60=0.021, MX60E=0.021, ZCB00=0.032, CTR10=0.121 gf), at 10.5mm (MX60=0.037, MX60E=0.040, ZCB00=0.041, CTR10=0.157 gf), at 10mm (MX60=0.094, MX60E=0.095, ZCB00=0.058, CTR10=0.176 gf), at 9.5mm (MX60=0.120, MX60E =0.091, ZCB00=0.078, CTR10=0.229 gf), and at 9.0mm (MX60=0.114, MX60E=0.114, ZCB00=0.103, CTR10=0.266 gf).

Conclusions : All varieties of IOLs and CTRs tested showed a trend towards a linear relationship between outward radial force and degree of compression, with the CTR averaging 316% more outward radial forces relative to average of the IOL group. MX60E demonstrated the highest outward radial force of all IOLs at 10mm (0.095 gf); 21.14% greater than ZCB00 and 54% of the total force of a CTR under similar conditions. Both MX60 and MX60E demonstrated greater capacity to direct compressive forces outward relative to ZCB00 with increasing degrees of compression (@9.5mm: MX60: +18.42%, MX60E: +5.86%; @9.0mm: MX60: +4.02%, MX60E: +4.09%). ZCB00 exhibited a propensity to deliver more outward force in the largest well configurations tested (@ 11mm: MX60: -9.06%, MX60E: -9.30%; @10.5mm: MX60: -3.13%, MX60E: -0.89%) owing to its larger overall diameter (13.0mm vs 12.5mm).

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

Outward Radial Compression Forces (gf) Measured Relative to Degree of Compression (mm)

Outward Radial Compression Forces (gf) Measured Relative to Degree of Compression (mm)

 

Compression Testing Apparatus Used to Measured Radial Forces per ISO 11979-3 Section 4.4 (Annex A)

Compression Testing Apparatus Used to Measured Radial Forces per ISO 11979-3 Section 4.4 (Annex A)

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