July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Extremely high resolution ocular aberrometry up to 2.4 million points
Author Affiliations & Notes
  • Sergio Bonaque-González
    Wooptix S.L., San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain
  • José Manuel Rodríguez-Ramos
    Wooptix S.L., San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain
  • Juan Manuel Trujillo-Sevilla
    Wooptix S.L., San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain
  • Oscar Casanova-González
    Wooptix S.L., San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain
  • David Carmona-Ballester
    Departamento de Ingeniería Industrial, Universidad de La Laguna, San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain
  • Miguel Jesús Sicilia-Cabrera
    Wooptix S.L., San Cristobal de La Laguna, Santa Cruz de Tenerife, Spain
  • Footnotes
    Commercial Relationships   Sergio Bonaque-González, Wooptix S.L. (E); José Rodríguez-Ramos, Wooptix S.L. (I); Juan Trujillo-Sevilla, Wooptix S.L. (E); Oscar Casanova-González, Wooptix S.L. (E); David Carmona-Ballester, Wooptix S.L. (S); Miguel Sicilia-Cabrera, Wooptix S.L. (E)
  • Footnotes
    Support  Fondo europeo de desarrollo regional de la comunidad autónoma de Canarias. Eatic2017010008
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 603. doi:
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      Sergio Bonaque-González, José Manuel Rodríguez-Ramos, Juan Manuel Trujillo-Sevilla, Oscar Casanova-González, David Carmona-Ballester, Miguel Jesús Sicilia-Cabrera; Extremely high resolution ocular aberrometry up to 2.4 million points. Invest. Ophthalmol. Vis. Sci. 2019;60(9):603.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : We present a new wavefront sensor (WFS) based in a deterministic approach for the propagation of light fields, able to recover the ocular aberrometry with the same resolution of the camera used. We report results of recovering aberrations of artificial eyes with a resolution above 2,400,000 points. Also, we show the first measurements of the optics of a human eye with as much resolution.

Methods : An artificial eye was placed as the object in an experimental double-pass WFS (prototype, Wooptix S.L–INTEL portfolio company, Spain). We calculate the photon displacement between two intensity images taken at different planes and the associated wavefront slope using geometrical optics approximations and the probability density function of photons.
A deformable mirror (DM) was placed in a plane conjugated with the pupil and commanded with 800 phase maps with amplitudes uniformly ranged between 0.35 and 2.8µm, in 0.35µm steps, and composed by random values of the first 66 Zernike polynomials. To validate our results, a Shack-Hartmann WFS (S-H) was placed in a parallel arm of the set-up.
Root Mean Square (RMS) errors were statistically analysed by means of the two-tailed student’s t-test. A real eye was placed into the system and its wavefront was also measured.

Results : The final measurement points within the pupil were 2,405,281 for the experimental WFS and 226 for the S-H. Remarkably, the higher resolution besides the proper dynamic range of the experimental WFS allowed to quantify, in one shot, the individual influence on the wavefront of each actuator of the DM as shown in figure 1.
The average RMS error with respect to the reference maps ranged between 0.06 and 0.08 for both WFS in all cases, showing the experimental WFS statistically better results. The average RMS difference between both WFS was -0.009±0.037. Measurement of the real eye was successfully performed.

Conclusions : We have developed a technology able to obtain an extremely high resolution wavefront phase map that exceeds by a large amount the current commercial methods. We experimentally validated such technology on synthetic samples as well as preliminarily tested it with a real human eye. This new technology could have a prominent utility in cataract and refractive surgery, in-vitro analysis of intraocular lenses and retina examination, among others.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

An example of the result of the experimental device beside the reference and Shack-Hartmann images.

An example of the result of the experimental device beside the reference and Shack-Hartmann images.

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