Abstract
Purpose :
The incidence of ptosis is known to be increased after a wide range of ocular surgeries. The purpose of this study is to investigate the relative incidence of postoperative ptosis among various ophthalmic procedures.
Methods :
In this case-control study, the relative prevalence of postsurgical ptosis in patients undergoing ocular surgery in a large population of adult patients was assessed. De-identified patient data from a 10-year period was obtained from the electronic medical records of five large academic health centers. Patients were selected based on ICD9 and ICD10 codes for involutional ptosis. Prior ocular surgery was determined based on CPT codes. Control patients were age and gender matched and randomly selected from among a general adult population presenting to one of the 5 centers. The influence of ocular surgery was examined utilizing logistic regression analysis.
Results :
The study cohort included a total of 8,297 patients with ptosis. The control group contained 13,128 matched controls. In these 2 groups, 1,837 patients underwent at least one ophthalmic surgery. Cataract surgery was the most common surgery performed, followed by cornea and glaucoma surgery (figure 1). Ocular surgery as a whole was identified as a significant risk factor for the development of ptosis, with an odds ratio of 5.31 (p<0.05). Of those patients with at least one ocular surgery, strabismus, cornea, and glaucoma surgeries were all found to be more highly associated with developing ptosis (p<0.05). Strabismus surgery had the greatest odds ratio of 3.37, followed by cornea surgery with 2.31 and glaucoma surgery with 1.56 (table 1). The model overall performed well with an area under the ROC curve of 0.66.
Conclusions :
Among patients with prior ocular surgery, the surgeries most highly associated with the development of ptosis were strabismus, cornea, and glaucoma.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.