Abstract
Purpose :
To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia.
Methods :
A total of 85 highly myopic eyes in 47children (6.3±3.6 years of age, range from 3years old to 15 years old) who underwent this modified PSR were included in this study. Axial length, refractive error, best corrected visual acuity (BCVA), macular scans and adverse events were recorded before the operation (as a baseline) and in postoperative reviews taken yearly for 5 years.
Results :
It was a 5-year term research, 50% children (20 children 40 eyes) participated the 6-month review, 41% children (17 children of 33 eyes) participated the 1-year review, 26% children (11 children of 21 eyes) participated the 2-year review, 16% children (7 children of 13 eyes) participated the 3-year review, 13% children (5.3 children of 11 eyes) participated the 4-year review, 8% children (3.3 children of 7 eyes) participated the 5-year review. Compared with the baseline, axial elongation was significant changed(P＜0.05) over the 5-year period in all of the children:6-month(P=0.003), 1-year(P=0), 2-year(P=0), 3-year(P=0), 4-year(P=0), 5-year(P=0). The axial length was extended. No significant difference was found in refractive error between measurements taken at baseline and at the 5-year postoperative visit in all of the children:6-month(P=0.51), 1-year(P=0.50), 2-year(P=0.46), 3-year(P=0.56), 4-year(P=0.30), 5-year(P=0.16). There were significant differences in BCVA between measurements taken at baseline and at the postoperative 5-year visit in all the children:.6-month(P=0), 1-year(P=0), 2-year(P=0), 3-year(P=0), 4-year(P=0), 5-year(P=0). BCVA improved in 71 eyes (83.52%), remained stable in 14 eyes (16.47%), and declined in none of the children. No serious adverse events occurred before the operation and during the 5-year follow-up period.
Conclusions :
This modified PSR could be a therapeutic treatment for high myopia.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.