July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Pediatric Ocular Surface Disease Associated with Suspected Abuse
Author Affiliations & Notes
  • Christine Shieh
    Vanderbilt Eye Institute, Nashville, Tennessee, United States
  • Mehak Aziz
    Vanderbilt Eye Institute, Nashville, Tennessee, United States
  • Minas T Coroneo
    Ophthalmology, Prince of Wales Hospital, New South Wales, Australia
  • Gerald W Zaidman
    Ophthalmology, New York Medical College, Valhalla, New York, United States
    Ophthalmology, Westchester Medical Center, Valhalla, New York, United States
  • Louise A Mawn
    Vanderbilt Eye Institute, Nashville, Tennessee, United States
  • Footnotes
    Commercial Relationships   Christine Shieh, None; Mehak Aziz, None; Minas Coroneo, None; Gerald Zaidman, None; Louise Mawn, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 924. doi:
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    • Get Citation

      Christine Shieh, Mehak Aziz, Minas T Coroneo, Gerald W Zaidman, Louise A Mawn; Pediatric Ocular Surface Disease Associated with Suspected Abuse. Invest. Ophthalmol. Vis. Sci. 2019;60(9):924.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Non-accidental injury (NAI) is a rare, but important, diagnosis to make in pediatric ocular surface disease. While in the absence of admission from a family member, it is impossible to make an absolutely conclusive diagnosis of NAI, the clinician needs to maintain a high degree of concern in unusual and recurring injuries. We describe, to our knowledge, the largest series to date of pediatric patients with ocular surface disease whose etiology was strongly suspected to be NAI.

Methods : Retrospective, multi-center case review.

Results : A wide spectrum of anterior segment findings have been noted in our case series and review of the literature. Our case series identifies both: (1) four cases where severe ocular surface disease (necessitating surgery), was presumed to be due to NAI, and (2) the ophthalmic findings of a pair of siblings whose keratitis was ultimately diagnosed by parental slit-lamp examination as related to inherited anterior basement membrane dystrophy. Our case series and literature review suggest that NAI is typically associated with bilateral and recurrent disease, and can also be marked by improvement that is better than expected during hospitalization.

Conclusions : In pediatric patients presenting with ocular surface disease suggestive of NAI, we recommend a thorough history and exam, including assessment of the patient’s corneal sensation, and a slit lamp examination of the parents. In the setting of ocular surface disease that does not respond to treatment, consideration should be given to whether the disease improves when the patient is hospitalized, away from family members.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

Table Summary of Patient Clinical and Demographic Details

Table Summary of Patient Clinical and Demographic Details

 

Clinical images from Case 1. External photographs of the right (A) and left (B) eyes, showing significant symblepharon, cornea opacification, and limbal stem cell deficiency.

Clinical images from Case 1. External photographs of the right (A) and left (B) eyes, showing significant symblepharon, cornea opacification, and limbal stem cell deficiency.

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