July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Comparison of Trends in Risk Factors for Retinopathy of Prematurity Over 12 years in Colorado: How One Academic Medical Center Compares to Statewide Data
Author Affiliations & Notes
  • Lauren Mehner
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Brandie D Wagner
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Kirk A Bol
    Colorado Department of Public Health and Environment, Colorado, United States
  • Jasleen K Singh
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Scott CN Oliver
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Emily A McCourt
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Jennifer Patnaik
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Alan Palestine
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Naresh Mandava
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Anne Lynch
    Ophthalmology, University of Colorado, Aurora, Colorado, United States
  • Footnotes
    Commercial Relationships   Lauren Mehner, None; Brandie Wagner, None; Kirk Bol, None; Jasleen Singh, None; Scott Oliver, None; Emily McCourt, None; Jennifer Patnaik, None; Alan Palestine, None; Naresh Mandava, None; Anne Lynch, None
  • Footnotes
    Support  Challenge Grant to the Department of Ophthalmology from Research to Prevent Blindness
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 6520. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Lauren Mehner, Brandie D Wagner, Kirk A Bol, Jasleen K Singh, Scott CN Oliver, Emily A McCourt, Jennifer Patnaik, Alan Palestine, Naresh Mandava, Anne Lynch; Comparison of Trends in Risk Factors for Retinopathy of Prematurity Over 12 years in Colorado: How One Academic Medical Center Compares to Statewide Data. Invest. Ophthalmol. Vis. Sci. 2019;60(9):6520. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : More infants are surviving who are born at the lower extremes of gestational age and birth weight. We previously investigated if this change in neonatal survival is impacting the rate of severe retinopathy of prematurity (ROP) among infants born at University of Colorado Hospital (UCH). We reported (ARVO 2017) no change in rates of severe ROP over a 12 year period in our cohort of infants born at risk for ROP. We wanted to investigate whether trends in ROP risk factors at our academic institution were representative of trends in ROP risk factors in the state of Colorado.

The purpose of our study was to expand our research and compare trends in risk factors for ROP in infants born at UCH (UCH cohort) and infants included in statewide data collected by the Colorado Department of Public Health and Environment (Colorado cohort).

Methods : This was a retrospective cohort study comparing the gestational age, birth weight, and mortality in all infants in Colorado to those at one academic institution (UCH) between January 2006 and December 2017. All infants in the study had a gestational age less than 31 weeks or birth weight less than 1500 grams.

Results : The UCH cohort included data from 1,378 infants who met the above birth weight or gestational age criteria. The Colorado cohort included 804,883 infants, 11,138 of whom met the above criteria. We found no significant trends in gestational age (slope estimate (SE): 0.02 (0.02), p = 0.35), birth weight (1.4 (2.6), p = 0.59) (Figure 1) or mortality rates (0.03 (0.03) p = 0.37) (Figure 2) over time in the UCH cohort. Similarly, we found no significant trends in these variables over time in the Colorado cohort. The proportion of infants meeting screening criteria was also stable over time in the Colorado cohort (fluctuating between 1.27% and 1.49%).

Conclusions : There was no significant difference in trends for gestational age, birth weight or death rates in either of the two cohorts over the 12 year period.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

 

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×