July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Hand-held high-speed whole-eye OCT: Simultaneous SSOCT of the anterior segment and retina using a compact probe
Author Affiliations & Notes
  • Al-Hafeez Dhalla
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
    Ophthalmology, Duke University Health System, Durham, North Carolina, United States
  • Ryan P McNabb
    Ophthalmology, Duke University Health System, Durham, North Carolina, United States
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
  • Pablo Ortiz
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
  • Moseph Jackson-Atogi
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
  • Gar Waterman
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
  • Joseph A Izatt
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
    Ophthalmology, Duke University Health System, Durham, North Carolina, United States
  • Anthony N Kuo
    Ophthalmology, Duke University Health System, Durham, North Carolina, United States
    Biomedical Engineering, Duke University, Chapel Hill, North Carolina, United States
  • Footnotes
    Commercial Relationships   Al-Hafeez Dhalla, Leica Microsystems (P), Leica Microsystems (R); Ryan McNabb, None; Pablo Ortiz, None; Moseph Jackson-Atogi, None; Gar Waterman, None; Joseph Izatt, Carl Zeiss Meditec (P), Carl Zeiss Meditec (R), Leica Microsystems (P), Leica Microsystems (R); Anthony Kuo, None
  • Footnotes
    Support  DOD/USAMRAA grant W81XWH-16-1-0498
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 1295. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Al-Hafeez Dhalla, Ryan P McNabb, Pablo Ortiz, Moseph Jackson-Atogi, Gar Waterman, Joseph A Izatt, Anthony N Kuo; Hand-held high-speed whole-eye OCT: Simultaneous SSOCT of the anterior segment and retina using a compact probe. Invest. Ophthalmol. Vis. Sci. 2019;60(9):1295. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Penetrating wounds to the eye require rapid assessment, as these injuries often require immediate surgical intervention to prevent permanent vision loss. Current clinical OCT systems are not well suited for triage following acute injury, as separate instruments are needed for anterior segment (AS) and retinal imaging, and require skilled operators and patient cooperation. We report on the development of a high-speed hand-held whole-eye OCT (HH-WEOCT) system that can be used to rapidly assess damage to both the AS and retina simultaneously in acute environments.

Methods : The engine of the HH-WEOCT system employs a VCSEL laser operating at 400kHz and 1059nm +/- 45nm. Laser output is directed to a fiber optic interferometer that employs both single mode and polarization maintaining fiber to produce two separate polarization-encoded channels. A-scans from both polarization channels (at effectively 800kHz) are processed, displayed and 3D rendered in real-time using custom software employing two GTX 1080 Ti GPUs.

A custom dual-channel hand-held probe was designed in which p- and s- polarized light are imaged onto the retina and anterior segment, respectively. The two paths are co-axial along parts of the optical train to share common elements (e.g. scanning mirrors), and separated in others to produce conjugate focal planes and allow for diopter control. The HH-WEOCT probe is protected by a rubberized, 3D-printed protective shell and integrates an iris camera and viewing monitor to aid with alignment.

Results : The retina imaging path of the HH-WEOCT probe design achieves a 40° FOV with diffraction-limited spots <19.5µm FWHM. The AS path produces <32.5µm FWHM diffraction-limited spots over the full corneal diameter (12.5mm). To demonstrate system performance, a model eye, consisting of an AR-coated lens corneal phantom and layered tape retinal phantom, was sequentially imaged.

Conclusions : We report on the first demonstration of a high-speed hand-held whole-eye OCT (HH-WEOCT) system designed for triage following acute ocular injury.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

 

Side (A) and front view (B) renderings of the HHP optomechanical design. Side (C) and rear view (D) photographs of the HHP with 3D printed shell and integrated viewing monitor.

Side (A) and front view (B) renderings of the HHP optomechanical design. Side (C) and rear view (D) photographs of the HHP with 3D printed shell and integrated viewing monitor.

 

Representative images acquired on a model eye. Top, AR-coated lens corneal phantom. Bottom, layered tape retinal phantom. Each image is a 10x average of 512 A-scans, acquired in 18msec.

Representative images acquired on a model eye. Top, AR-coated lens corneal phantom. Bottom, layered tape retinal phantom. Each image is a 10x average of 512 A-scans, acquired in 18msec.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×