Abstract
Purpose :
The aim of this study is to analyze imaging of corneal neovascularization using a spectral domain optical coherence tomography angiography (AS-OCTA) adapted to evaluate anterior segment.
Methods :
This is Cases series of 12 eyes of 10 patients with corneal neovascularizaitonfrom Escola Paulista de Medicina and Centro Oftalmológico São Paulo. The causes of corneal neovascularization included are Lipid Degeneration (1) , Corneal Transplant (6), Corneal Burns(1) , Staphylococcal Blepharitis (1) , Scleral Contact Lens Users (2) and Infectious Keratitis (1). Imagingwasperformed using a prototype anterior segment (PrototypeB) lens mounted on a spectral domain OCT, the CIRRUS™ HD-OCT 5000 withAngioPlex® OCT Angiography(ZEISS, Dublin, CA). The OCT angiography 3x3 mm scan pattern was used for vasculature imaging, after adjusting the focus of the scan by 10D, resulting in an estimated field of view at the front of the eye of 4mm by 4mm. Eye tracking was turned off to facilitate rapid capture. Manual re-segmentation afterc apture was performed on the images when necessary. Images of the four quadrants (nasal, temporal, inferior and superior) of the eye were taken.Quality of the images as well as the possibility of documentation of the depth of the vessels was analyzed
Results :
CIRRUS™ HD-OCT 5000 withAngioPlex® OCTAngiography– PrototypeBallowed the documentation of corneal neovascularization in cases studied in all quadrants studied
It was also possible to determine the depth, extension of the neovascular area with details and to follow the improvement or worsening of corneal neovascularization. The eye tracking was turned off so it was not possible to compare exactly the same area.
Conclusions :
CIRRUS™ HD-OCT 5000 withAngioPlex® OCTAngiography - PrototypeBadapted to the anterior segment demonstrated to be an easy and applicable imaging method to study and follow corneal neovascularization.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.